Sema Yimeslal Atnafu, Waktola Teshale Areda
School of Biological Sciences and Biotechnolog, Haramaya University, 138 Dire Dawa, Haramaya, Ethiopia.
FEMS Microbes. 2022 Jan 12;3:xtac001. doi: 10.1093/femsmc/xtac001. eCollection 2022.
In Ethiopia, the impacts of malaria continue to cause a many number of morbidity and mortality that accounts to most-outpatient observations. Ethiopia recently designed to attain nationwide malaria control by 2030 by beginning sub-national elimination in districts with low malaria transmission. However, the rise of drug-resistant parasites, especially hinder the malaria-containment strategies. and are dispersed all over Ethiopia, and account for 60% and 40% of malaria cases, respectively. The aim of this report was to overview the phytochemical constituents, diversity, and effect of some compound extracts on drug-resistant plasmodium species. Many plant species, a total 200 identified by 82 studies, are used in traditional malaria treatments throughout the country. , and were the more frequently used medicinal plant species. There are so many phytochemical constituents found in medicinal plants used to treat malaria. Alkaloids, flavonoids, phenolics, terpenoids, and glycosides are the most-reported for their effective activity on drug-resistant malaria.
在埃塞俄比亚，疟疾的影响继续导致大量发病和死亡，占大多数门诊观察病例。埃塞俄比亚最近计划到2030年实现全国疟疾控制，首先在疟疾传播率低的地区进行次国家级消除。然而，耐药寄生虫的出现尤其阻碍了疟疾控制策略。[两种耐药寄生虫名称未给出]在埃塞俄比亚各地均有分布，分别占疟疾病例的60%和40%。本报告的目的是概述一些复合提取物的植物化学成分、多样性及其对耐药疟原虫物种的作用。全国共有82项研究鉴定出200种植物物种用于传统疟疾治疗。[三种常用药用植物名称未给出]是使用频率较高的药用植物物种。用于治疗疟疾的药用植物中发现了许多植物化学成分。生物碱、黄酮类化合物、酚类、萜类和糖苷因其对耐药疟疾的有效活性而被报道最多。
