Low-Field Combined Diffusion-Relaxation MRI for Mapping Placenta Structure and Function.

PURPOSE

Demonstrating quantitative multi-parametric mapping in the placenta with combined -diffusion MRI at low-field (0.55T).

METHODS

We present 57 placental MRI scans performed on a commercially available 0.55T scanner. We acquired the images using a combined -diffusion technique scan that simultaneously acquires multiple diffusion preparations and echo times. We processed the data to produce quantitative and diffusivity maps using a combined -ADC model. We compared the derived quantitative parameters across gestation in healthy controls and a cohort of clinical cases.

RESULTS

Quantitative parameter maps closely resemble those from previous experiments at higher field strength, with similar trends in and ADC against gestational age observed.

CONCLUSION

Combined -diffusion placental MRI is reliably achievable at 0.55T. The advantages of lower field strength - such as cost, ease of deployment, increased accessibility and patient comfort due to the wider bore, and increased for larger dynamic ranges - can support the widespread roll out of placental MRI as an adjunct to ultrasound during pregnancy.