Wu Jiawen, Wang Yuzhu, Wang Lu, Wu Hengjing, Li Jue, Zhang Lijuan
Clinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Tongji University, Shanghai, China.
Front Psychiatry. 2023 May 12;14:1169502. doi: 10.3389/fpsyt.2023.1169502. eCollection 2023.
We aimed to elucidate trends in the crude mortality rate (CMR), age-standardized mortality rate (ASMR), and burden of mental disorders (MD) in China.
A longitudinal observational study was performed using the data of MD deaths in the National Disease Surveillance System (DSPs) during 2009-2019. The mortality rates were normalized using the Segis global population. Trends in the mortality of MDs stratified by age, gender, region, and residency, respectively. The burden of MD was evaluated using age-standardized person years of life loss per 100,000 people (SPYLLs) and average years of life lost (AYLL).
A total of 18,178 MD deaths occurred during 2009-2019, accounting for 0.13% of total deaths, and 68.3% of MD deaths occurred in rural areas. The CMR of MD in China was 0.75/100,00 persons (ASMR: 0.62/100,000 persons). The ASMR of all MDs decreased mainly due to the decrease in ASMR in rural residents. Schizophrenia and alcohol use disorder (AUD) were the leading causes of death in MD patients. The ASMR of schizophrenia and AUD was higher in rural residents than in urban residents. The ASMR of MD was highest in the 40-64 age group. As the leading causes of MD burden, the SPYLL and AYLL of schizophrenia were 7.76 person-years and 22.30 years, respectively.
Although the ASMR of all MDs decreased during 2009-2019, schizophrenia and AUD were still the most important causes of death for MDs. Targeted efforts focusing on men, rural residents, and the 40-64 years old population should be strengthened to decrease MD-related premature deaths.
我们旨在阐明中国粗死亡率(CMR)、年龄标准化死亡率(ASMR)和精神障碍(MD)负担的趋势。
利用2009 - 2019年国家疾病监测系统(DSPs)中MD死亡数据进行纵向观察性研究。死亡率采用Segis全球人口进行标准化。分别按年龄、性别、地区和居住地对MD死亡率趋势进行分层。MD负担采用每10万人年龄标准化寿命损失人年数(SPYLLs)和平均寿命损失年数(AYLL)进行评估。
2009 - 2019年期间共发生18178例MD死亡,占总死亡人数的0.13%,68.3%的MD死亡发生在农村地区。中国MD的CMR为0.75/10万人(ASMR:0.62/10万人)。所有MD的ASMR下降主要是由于农村居民ASMR的下降。精神分裂症和酒精使用障碍(AUD)是MD患者的主要死亡原因。农村居民中精神分裂症和AUD的ASMR高于城市居民。MD的ASMR在40 - 64岁年龄组最高。作为MD负担的主要原因,精神分裂症的SPYLL和AYLL分别为7.76人年和22.30年。
尽管2009 - 2019年期间所有MD的ASMR有所下降,但精神分裂症和AUD仍是MD最重要的死亡原因。应加强针对男性、农村居民和40 - 64岁人群的针对性努力,以减少与MD相关的过早死亡。