Lacey Randy F, Fairhurst Michael J, Daley Kaitlyn J, Ngata-Aerengamate Te Amohaere, Patterson Haileigh R, Patrick Wayne M, Gerth Monica L
Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand.
FEMS Microbes. 2021 Nov 18;2:xtab016. doi: 10.1093/femsmc/xtab016. eCollection 2021.
species cause disease and devastation of plants in ecological and horticultural settings worldwide. A recently identified species, , infects and ultimately kills the treasured kauri trees () that are endemic to New Zealand. Currently, there are few options for managing kauri dieback disease. In this study, we sought to assess the efficacy of the oomycide oxathiapiprolin against several life cycle stages of two geographically distinct isolates. The effective concentration to inhibit 50% of mycelial growth (EC) was determined to be ∼0.1 ng/ml, indicating that mycelia are more sensitive to oxathiapiprolin than those from most other species that have been studied. Oxathiapiprolin was also highly effective at inhibiting the germination of zoospores (EC = 2-9 ng/ml for the two isolates) and oospores (complete inhibition at 100 ng/ml). In addition, oxathiapiprolin delayed the onset of detached kauri leaf infection in a dose-dependent manner. Collectively, the results presented here highlight the significant potential of oxathiapiprolin as a tool to aid in the control of kauri dieback disease.
多种病原菌在全球生态和园艺环境中导致植物病害和破坏。最近鉴定出的一种病原菌，感染并最终杀死了新西兰特有的珍贵贝壳杉树（）。目前，治理贝壳杉枯梢病的方法很少。在本研究中，我们试图评估卵菌纲杀菌剂恶唑菌酮对两个地理上不同的分离株的几个生命周期阶段的防治效果。抑制50%菌丝生长的有效浓度（EC）被确定为约0.1 ng/ml，这表明该病原菌的菌丝体比大多数其他已研究的病原菌的菌丝体对恶唑菌酮更敏感。恶唑菌酮在抑制游动孢子萌发（两个分离株的EC = 2 - 9 ng/ml）和卵孢子萌发（100 ng/ml时完全抑制）方面也非常有效。此外，恶唑菌酮以剂量依赖的方式延迟了离体贝壳杉树叶感染的发生。总体而言，此处呈现的结果突出了恶唑菌酮作为一种有助于控制贝壳杉枯梢病的工具的巨大潜力。
