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马拉维恩诺的去中心化心力衰竭管理。

Decentralized Heart Failure Management in Neno, Malawi.

机构信息

Partners In Health/Abwenzi Pa Za Umoyo, Neno, Malawi.

Partners In Health, Boston, MA, 02199, USA.

出版信息

Glob Heart. 2023 Jun 16;18(1):35. doi: 10.5334/gh.1210. eCollection 2023.

DOI:10.5334/gh.1210
PMID:37334396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10275181/
Abstract

BACKGROUND

Cardiovascular disease (CVD) is a major cause of death in Malawi. In rural districts, heart failure (HF) care is limited and provided by non-physicians. The causes and patient outcomes of HF in rural Africa are largely unknown. In our study, non-physician providers performed focused cardiac ultrasound (FOCUS) for HF diagnosis and longitudinal clinical follow-up in Neno, Malawi.

OBJECTIVES

We described the clinical characteristics, HF categories, and outcomes of patients presenting with HF in chronic care clinics in Neno, Malawi.

METHODS

Between November 2018 and March 2021, non-physician providers performed FOCUS for diagnosis and longitudinal follow-up in an outpatient chronic disease clinic in rural Malawi. A retrospective chart review was performed for HF diagnostic categories, change in clinical status between enrollment and follow-up, and clinical outcomes. For study purposes, cardiologists reviewed all available ultrasound images.

RESULTS

There were 178 patients with HF, a median age of 67 years (IQR 44 - 75), and 103 (58%) women. During the study period, patients were enrolled for a mean of 11.5 months (IQR 5.1-16.5), after which 139 (78%) were alive and in care. The most common diagnostic categories by cardiac ultrasound were hypertensive heart disease (36%), cardiomyopathy (26%), and rheumatic, valvular or congenital heart disease (12.3%).At follow-up, the proportion of New York Heart Association (NYHA) class I patients increased from 24% to 50% (p < 0.001; 95% CI: 31.5 - 16.4), and symptoms of orthopnea, edema, fatigue, hypervolemia, and bibasilar crackles all decreased (p < 0.05).

CONCLUSION

Hypertensive heart disease and cardiomyopathy are the predominant causes of HF in this elderly cohort in rural Malawi. Trained non-physician providers can successfully manage HF to improve symptoms and clinical outcomes in limited resource areas. Similar care models could improve healthcare access in other rural African settings.

摘要

背景

心血管疾病(CVD)是马拉维的主要死亡原因。在农村地区,心力衰竭(HF)的治疗由非医师提供,且十分有限。农村非洲心力衰竭的病因和患者结局在很大程度上尚不清楚。在我们的研究中,在马拉维的 Neno,非医师提供者为 HF 诊断和纵向临床随访执行了焦点心脏超声(FOCUS)。

目的

我们描述了在马拉维农村 Neno 的慢性护理诊所就诊的 HF 患者的临床特征、HF 类别和结局。

方法

2018 年 11 月至 2021 年 3 月期间,非医师提供者在农村马拉维的一家门诊慢性疾病诊所进行 FOCUS 诊断和纵向随访。对 HF 诊断类别、入组和随访之间临床状况的变化以及临床结局进行回顾性图表审查。出于研究目的,心脏病专家审查了所有可用的超声图像。

结果

共有 178 例 HF 患者,中位年龄为 67 岁(IQR 44-75),103 例(58%)为女性。在研究期间,患者的平均入组时间为 11.5 个月(IQR 5.1-16.5),之后 139 例(78%)存活并接受治疗。心脏超声最常见的诊断类别为高血压性心脏病(36%)、心肌病(26%)和风湿性、瓣膜性或先天性心脏病(12.3%)。随访时,纽约心脏协会(NYHA)I 级患者的比例从 24%增加到 50%(p<0.001;95%CI:31.5-16.4),呼吸困难、水肿、疲劳、血容量过多和双基底部爆裂声的症状均有所改善(p<0.05)。

结论

在马拉维农村的这个老年队列中,高血压性心脏病和心肌病是 HF 的主要原因。经过培训的非医师提供者可以成功管理 HF,以改善有限资源地区的症状和临床结局。类似的护理模式可以改善其他农村非洲地区的医疗保健服务可及性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/7657020f22d2/gh-18-1-1210-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/3be9ecd96191/gh-18-1-1210-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/b8f0baf8e19d/gh-18-1-1210-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/7657020f22d2/gh-18-1-1210-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/3be9ecd96191/gh-18-1-1210-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/b8f0baf8e19d/gh-18-1-1210-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51df/10275181/7657020f22d2/gh-18-1-1210-g3.jpg

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2
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BMJ Glob Health. 2021 Sep;6(9). doi: 10.1136/bmjgh-2021-006535.
3
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5
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