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[通过测量被动电加和效应相对于电泳迁移率测试来识别对肿瘤抗原的特异性致敏作用的研究]

[Studies on the recognition of specific sensitization to tumor antigens by measuring passive electrical additive effects as against the electrophoretic mobility test].

作者信息

Emmrich F, Pliquett F, Wunderlich S, Irmscher I, Kotzsch M

出版信息

Acta Biol Med Ger. 1978;37(8):1267-72.

PMID:373346
Abstract

Lymphocytes from cancer patients were incubated with different tumor antigens. In the medium in which the lymphocytes were suspended, passive electrical values could be measured in the Mc region. These values correlate with a specific sensibilization of tumor carriers. By comparison with the electrophoresis-mobility test (em-test) we found in 66 out of 74 supernatants, using CEA and KCl-extracts as antigens, a good conformity of the two reaction patterns.

摘要

将癌症患者的淋巴细胞与不同的肿瘤抗原一起培养。在淋巴细胞悬浮的培养基中,可以在Mc区域测量被动电值。这些值与肿瘤携带者的特异性致敏相关。通过与电泳迁移率试验(em试验)比较,我们发现,以癌胚抗原(CEA)和氯化钾提取物作为抗原时,在74份上清液中的66份中,两种反应模式具有良好的一致性。

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