来自荨麻青霉突变体S11R59的新型大环内酯类化合物。

New macrolides from Penicillium urticae mutant S11R59.

作者信息

Rodphaya D, Sekiguchi J, Yamada Y

出版信息

J Antibiot (Tokyo). 1986 May;39(5):629-35. doi: 10.7164/antibiotics.39.629.

DOI:10.7164/antibiotics.39.629

Abstract

Two new macrolides, patulolide B and patulolide C, were isolated from a culture filtrate of Penicillium urticae S11R59 mutant. The structures of these macrolides were determined and their biological activities were investigated. These structures and biological activities were also compared with those of patulolide A which was produced by the same organism.

摘要

从荨麻青霉S11R59突变体的培养滤液中分离出两种新的大环内酯类化合物，即patulolide B和patulolide C。确定了这些大环内酯类化合物的结构，并对其生物活性进行了研究。还将这些结构和生物活性与由同一生物体产生的patulolide A的结构和生物活性进行了比较。