Bisno Daniel I, Reid Mark W, Pyatak Elizabeth A, Flores Garcia Jaquelin, Salcedo-Rodriguez Elizabeth, Torres Sanchez Alejandra, Fox D Steven, Hiyari Sarah, Fogel Jennifer L, Marshall Ian, Bachmann Gloria, Raymond Jennifer K
Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Children's Hospital Los Angeles, Los Angeles, California, USA.
Diabetes Technol Ther. 2023 Sep;25(9):589-601. doi: 10.1089/dia.2023.0199. Epub 2023 Aug 17.
Adolescents and young adults (AYA) from diverse and marginalized backgrounds with type 1 diabetes (T1D) generally have higher hemoglobin A1c (HbA1c) levels and less frequent continuous glucose monitor (CGM) use than AYA from more privileged backgrounds. Further, scant data address the impact of virtual peer groups (VPG) on health-related outcomes for ethnically and racially diverse AYA with T1D. CoYoT1 to California was a 15-month randomized controlled trial for AYA aged 16-25 years. In this study, AYA were randomized to receive standard care ( = 28), or CoYoT1 care ( = 40), which consisted of person-centered provider visits and bimonthly VPG. VPG were AYA-driven discussions. AYA completed the Diabetes Distress Scale (DDS), Center for Epidemiologic Studies Depression (CES-D), and Diabetes Empowerment Scale-Short Form (DES-SF) scales at baseline and all study visits. Participants were 50% Latinx and 75% publicly insured. Among CoYoT1 care participants, 19 attended at least 1 VPG session (VPG attendees) and 21 did not attend any VPG sessions. VPG attendees participated in 4.1 VPG sessions on average. VPG attendees had a relative reduction in HbA1C (treatment effect -1.08%, effect sizes values [ES] = -0.49, = 0.04) and increase in CGM use (treatment effect +47%, ES = 1.00, = 0.02) compared to standard care. VPG participation was not associated with statistically significant changes in DDS, CES-D, and DES-SF scores. In a 15-month randomized controlled trial, AYA with T1D who participated in VPG reported significant improvements in HbA1c and CGM use. Peer interactions may support unmet needs of AYA with T1D from diverse and marginalized backgrounds. ClinicalTrials.gov Identifier: NCT03793673.
与背景更优越的青少年和青年成年人(AYA)相比,来自不同和边缘化背景且患有1型糖尿病(T1D)的AYA通常糖化血红蛋白(HbA1c)水平更高,连续血糖监测(CGM)的使用频率更低。此外,关于虚拟同伴群体(VPG)对不同种族和族裔的T1D患者健康相关结局的影响的数据很少。CoYoT1到加利福尼亚州是一项针对16至25岁AYA的为期15个月的随机对照试验。在本研究中,AYA被随机分为接受标准护理(n = 28)或CoYoT1护理(n = 40),CoYoT1护理包括以患者为中心的医护人员问诊和每两个月一次的VPG。VPG是由AYA主导的讨论。AYA在基线和所有研究访视时完成糖尿病痛苦量表(DDS)、流行病学研究中心抑郁量表(CES-D)和糖尿病自我效能感量表简表(DES-SF)。参与者中50%为拉丁裔,75%有公共保险。在CoYoT1护理参与者中,19人至少参加了1次VPG会议(VPG参会者),21人未参加任何VPG会议。VPG参会者平均参加了4.1次VPG会议。与标准护理相比,VPG参会者的HbA1C相对降低(治疗效果-1.08%,效应量[ES]=-0.49,P = 0.04),CGM使用增加(治疗效果+47%,ES = 1.00,P = 0.02)。VPG参与与DDS、CES-D和DES-SF评分的统计学显著变化无关。在一项为期15个月的随机对照试验中,参与VPG的T1D患者报告其HbA1c和CGM使用有显著改善。同伴互动可能有助于满足来自不同和边缘化背景的T1D患者未得到满足的需求。ClinicalTrials.gov标识符:NCT03793673。