Suppr超能文献

早期三阴性乳腺癌之旅:起点、终点及其间的一切。

Early-Stage Triple-Negative Breast Cancer Journey: Beginning, End, and Everything in Between.

机构信息

Department of Breast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

The University of Iowa Holden Comprehensive Cancer Center, Iowa City, IA.

出版信息

Am Soc Clin Oncol Educ Book. 2023 Jun;43:e390464. doi: 10.1200/EDBK_390464.

Abstract

Triple-negative breast cancer (TNBC) is a very heterogeneous and aggressive breast cancer subtype with a high risk of mortality, even if diagnosed early. The mainstay of early-stage breast cancer includes systemic chemotherapy and surgery, with or without radiation therapy. More recently, immunotherapy is approved to treat TNBC, but managing immune-rated adverse events while balancing efficacy is a challenge. The purpose of this review is to highlight the current treatment recommendations for early-stage TNBC and the management of immunotherapy toxicities.

摘要

三阴性乳腺癌(TNBC)是一种非常异质性和侵袭性的乳腺癌亚型,即使早期诊断,死亡率也很高。早期乳腺癌的主要治疗方法包括全身化疗和手术,可辅以或不辅以放疗。最近,免疫疗法被批准用于治疗 TNBC,但在平衡疗效的同时管理免疫相关不良事件是一个挑战。本文旨在强调早期 TNBC 的当前治疗建议和免疫治疗毒性的管理。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验