Astrand P O, Hultman E, Juhlin-Dannfelt A, Reynolds G
J Appl Physiol (1985). 1986 Jul;61(1):338-43. doi: 10.1152/jappl.1986.61.1.338.
Heavy dynamic exercise using both arm and leg muscles was performed to exhaustion by seven well-trained subjects. The aerobic and anaerobic energy utilization was determined and/or calculated. O2 uptake during exercise and during 1 h of recovery was measured as well as splanchnic and muscle metabolite exchange. Glycogen and lactate content in the quadriceps femoris was determined before exercise, immediately after exercise, and after a recovery period. In four male subjects the estimated mean lactate production during exercise was 830 mmol. The splanchnic uptake of lactate during recovery was 80 mmol, and the calculated maximum amount oxidized during the recovery period was 330 mmol. About 60 mmol were accounted for in the body water at the end of the rest period. The remaining 360 mmol of lactate were apparently resynthesized into glycogen in muscle via gluconeogenesis. It is concluded that approximately 50% of the lactate formed during heavy exercise is transformed to glycogen via glyconeogenesis in muscle during recovery and that lactate uptake by the liver is only 10%.
七名训练有素的受试者进行了使用手臂和腿部肌肉的剧烈动态运动，直至精疲力竭。测定和/或计算了有氧和无氧能量利用情况。测量了运动期间及恢复1小时期间的氧气摄取量，以及内脏和肌肉代谢物交换情况。在运动前、运动后即刻以及恢复期后测定股四头肌中的糖原和乳酸含量。在四名男性受试者中，运动期间估计的平均乳酸生成量为830毫摩尔。恢复期间内脏对乳酸的摄取量为80毫摩尔，计算得出恢复期内氧化的最大量为330毫摩尔。休息期结束时，约60毫摩尔存在于体内水中。其余360毫摩尔的乳酸显然通过糖异生在肌肉中重新合成糖原。结论是，剧烈运动期间形成的乳酸中约50%在恢复期间通过肌肉中的糖异生转化为糖原，而肝脏对乳酸的摄取仅为10%。
