Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, K1N 6N5, Canada.
J Mater Chem B. 2023 Jul 5;11(26):6114-6122. doi: 10.1039/d3tb00199g.
In this work, we outline a simple method for synthesizing decahedral and triangular silver nanoparticles using light to tune particle shape and spectral characteristics. Notably, we were able to generate triangular silver nanoparticles with exceptional absorbance in the near-infrared (NIR) region, with high spectral overlap with the biological window, making them particularly promising for biological applications. We further demonstrate that under complementary LED illumination, these excitable plasmonic particles display exceptional antibacterial properties, several orders of magnitude more potent than similar particles under dark conditions or under illumination that does not match particle absorbance. This work demonstrates the powerful effects that LED lights can have on the antibacterial activity of AgNPs, providing an inexpensive and easily implemented route to unlocking the full potential of AgNPs in photobiological applications.
在这项工作中，我们概述了一种使用光来调整颗粒形状和光谱特性来合成十面体和三角形银纳米粒子的简单方法。值得注意的是，我们能够生成具有优异近红外（NIR）区域吸收能力的三角形银纳米粒子，与生物窗口具有很高的光谱重叠，这使得它们在生物应用中特别有前途。我们进一步证明，在互补的 LED 照明下，这些可激发等离子体粒子表现出异常的抗菌特性，比在黑暗条件下或在不匹配粒子吸收的照明下的类似粒子强几个数量级。这项工作证明了 LED 灯对 AgNPs 抗菌活性的强大影响，为在光生物应用中充分发挥 AgNPs 的潜力提供了一种廉价且易于实施的途径。
