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创伤作为基底细胞癌的一种可能病因。

Trauma as a possible etiologic factor in basal cell carcinoma.

作者信息

Noodleman F R, Pollack S V

出版信息

J Dermatol Surg Oncol. 1986 Aug;12(8):841-6. doi: 10.1111/j.1524-4725.1986.tb01991.x.

Abstract

1774 basal cell carcinoma lesions treated by Mohs surgery between 1979 and 1986 were evaluated for previous trauma histories. These traumas include burns, sharp trauma, chicken pox scars, blunt trauma, and vaccinations. 129 (7.3%) had a previous history of trauma. Analysis revealed that patients with trauma-related tumors were slightly younger and more likely to be male. Their lesions were larger pre- and post-op, and more often required five or more Mohs surgery stages, indicating these tumors may be especially deceptive clinically. The tumors were not particularly aggressive judging by histologic type. The literature is reviewed and implications for future work suggested.

摘要

对1979年至1986年间接受莫氏手术治疗的1774例基底细胞癌病变进行了既往创伤史评估。这些创伤包括烧伤、锐器伤、水痘疤痕、钝器伤和疫苗接种。129例(7.3%)有既往创伤史。分析显示,与创伤相关肿瘤的患者年龄稍小,男性居多。他们的病变在术前和术后更大,并且更常需要五个或更多的莫氏手术阶段,这表明这些肿瘤在临床上可能特别具有欺骗性。从组织学类型判断,这些肿瘤并非特别具有侵袭性。本文对相关文献进行了综述,并提出了对未来工作的启示。

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