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眼下细纹:一项关于线性基底细胞癌的大型前瞻性病例系列研究。

Lines under the eyes: a large prospective case series of linear basal cell carcinomas.

作者信息

Rutkowski D, Collier N J, Telfer N, Ghura V

机构信息

Mohs Unit, Department of Dermatology, Salford Royal Hospital NHS Foundation Trust, Northern Care Alliance NHS Group, Salford, England.

Dermatology Research Centre, NIHR Biomedical Research Centre, University of Manchester, Manchester, UK.

出版信息

Arch Dermatol Res. 2023 Apr;315(3):621-624. doi: 10.1007/s00403-022-02385-5. Epub 2022 Aug 12.

Abstract

Basal cell carcinomas (BCC) are the most common form of cancer globally. Linear BCCs are an unusual variant which are generally defined by having a length three times longer than the width and exhibiting relatively straight edges. In this report, we describe the largest global cohort (n = 31) with this rare subtype. Within this cohort, 22 were in the periocular region, 27 underwent Mohs micrographic surgery and 12 involved oculoplastic reconstruction. These results suggest that, whilst this subtype is relatively rare, it may be more prevalent than previously thought. Dermatologists and other specialities managing skin cancer, particularly ophthalmologists, should, therefore, be aware of this subtype, as it is often more aggressive than other BCC subtypes, often requiring multi-disciplinary management.

摘要

基底细胞癌(BCC)是全球最常见的癌症形式。线状基底细胞癌是一种不寻常的变体,通常定义为长度比宽度长三倍且边缘相对笔直。在本报告中,我们描述了全球最大的这一罕见亚型队列(n = 31)。在该队列中,22例位于眼周区域,27例接受了莫氏显微外科手术,12例涉及眼整形重建。这些结果表明,虽然这种亚型相对罕见,但可能比之前认为的更为普遍。因此,皮肤科医生和其他治疗皮肤癌的专科医生,尤其是眼科医生,应该了解这种亚型,因为它通常比其他基底细胞癌亚型更具侵袭性,常常需要多学科管理。

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