Mannering D, Bennett E D, Mehta N, Davis A L
Intensive Care Med. 1986;12(3):143-6. doi: 10.1007/BF00254929.
We have studied the haemodynamic effects of the application of the medical anti-shock trouser (MAST) in 10 healthy subjects in the semi-upright position in order to simulate mild hypovolaemia. Left ventricular end diastolic dimension (EDD) was measured by M-mode echocardiography and cardiac output (CO) by the Doppler ultrasound technique. Forearm blood flow (FBF) was measured by plethysmography and blood pressure (BP) by the standard cuff technique. Systematic increases in MAST pressure of up to 80 mm Hg were applied. EDD increased to a maximum of 9.3% (p less than or equal to 0.01) which was associated with a maximum increase in CO of 31.7% (p less than or equal to 0.05). FBF increased by a maximum of 54.2% (p less than or equal to 0.001) whilst BP increased by a maximum of 12% (p less than or equal to 0.001). These results demonstrate that the application of the MAST is an effective means of transferring blood to the central circulation by compression of the capacitance vessels resulting in significant increases in cardiac output and tissue perfusion. At high pressures there was evidence of compression of resistance vessels, which may be useful in reducing blood loss. The ease and rapidity with which his suit can be applied suggests that it may be useful in the short term treatment of hypovolaemia.
为模拟轻度低血容量状态，我们对10名半直立位的健康受试者应用医用抗休克裤（MAST）后的血流动力学效应进行了研究。通过M型超声心动图测量左心室舒张末期内径（EDD），采用多普勒超声技术测量心输出量（CO）。通过体积描记法测量前臂血流量（FBF），采用标准袖带技术测量血压（BP）。MAST压力系统性升高至80毫米汞柱。EDD最大增加9.3%（p≤0.01），同时CO最大增加31.7%（p≤0.05）。FBF最大增加54.2%（p≤0.001），而BP最大增加12%（p≤0.001）。这些结果表明，应用MAST是通过压迫容量血管将血液转移至中心循环的有效手段，可显著增加心输出量和组织灌注。在高压状态下，有证据表明阻力血管受到压迫，这可能有助于减少失血。该装置应用简便快捷，提示其在低血容量的短期治疗中可能有用。
