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耳鼻咽喉科手术中气管内导管套囊的压力变化:一项前瞻性观察研究。

Pressure changes in the endotracheal tube cuff in otorhinolaryngologic surgery: a prospective observational study.

作者信息

Park Sujung, Kwon Young In, Kim Hyun Joo

机构信息

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Front Med (Lausanne). 2023 Jun 5;10:1161566. doi: 10.3389/fmed.2023.1161566. eCollection 2023.

Abstract

OBJECTIVE

Inflation of the endotracheal tube cuff is needed for providing ventilation. Cuff pressure should be maintained inside the appropriate range to prevent critical airway complications. The purpose of this study is to evaluate the pressure changes in the endotracheal tube cuff during otorhinolaryngologic surgery.

DESIGN AND METHOD

This single-center observational study was conducted at Severance Hospital in Korea between April 2020 and November 2020. Patients aged >20 years scheduled to undergo otorhinolaryngological surgical procedures were enrolled. Patients undergoing planned tracheostomy and those who were slated for uncuffed endotracheal tube use were excluded. Intubation was performed after the induction of general anesthesia. A pressure transducer was connected to the pilot balloon of the endotracheal tube, and cuff pressure was continuously monitored until extubation. If the cuff pressure was not appropriate for more than 5 min, it was adjusted to the appropriate range by injecting or removing air. The percentage of time for which the cuff pressure remained within the appropriate range was calculated and defined as the time in the therapeutic range (TTR). The presumed cause for the rise or fall in cuff pressure was identified.

RESULTS

In total 199 patients, alterations in cuff pressure outside the appropriate range occurred in 191 patients (96.0%). The mean TTR was 79.7% (SD 25.0%), and head and neck surgery had the lowest mean TTR of 69.0% compared to ear and nose surgeries (94.2 and 82.1%, respectively). Sixty-eight patients (34.2%) demonstrated inadequate endotracheal tube cuff pressure for more than 20% of the total anesthesia time. Twenty-six patients (13.1%) demonstrated optimal endotracheal tube cuff pressure for less than 50% of the total anesthesia time. The causative factors inducing inappropriate cuff pressure were found to vary, including positional changes, surgical procedure, anatomical manipulation, and anesthetic procedure.

CONCLUSION

In otorhinolaryngologic surgery, cuff pressure increased or decreased outside the appropriate range due to various factors. Therefore, we suggest close continuous monitoring of cuff pressure during anesthesia for otorhinolaryngologic surgery.

CLINICAL TRIAL REGISTRATION

clinicaltrials.gov, identifier NCT03938493.

摘要

目的

气管内插管套囊充气是提供通气所必需的。套囊压力应维持在适当范围内,以防止严重气道并发症。本研究的目的是评估耳鼻咽喉科手术期间气管内插管套囊的压力变化。

设计与方法

本单中心观察性研究于2020年4月至2020年11月在韩国延世大学Severance医院进行。纳入年龄>20岁、计划接受耳鼻咽喉科手术的患者。排除计划行气管切开术的患者以及预定使用无套囊气管内插管的患者。全身麻醉诱导后进行插管。将压力传感器连接到气管内插管的指示球囊,并持续监测套囊压力直至拔管。如果套囊压力在5分钟以上不合适,则通过注入或抽出空气将其调整到适当范围。计算套囊压力保持在适当范围内的时间百分比,并将其定义为治疗范围内时间(TTR)。确定套囊压力升高或降低的推测原因。

结果

总共199例患者中,191例患者(96.0%)出现套囊压力在适当范围之外的变化。平均TTR为79.7%(标准差25.0%),与耳部和鼻部手术相比,头颈外科手术的平均TTR最低,为69.0%(耳部手术和鼻部手术分别为94.2%和82.1%)。68例患者(34.2%)在总麻醉时间的20%以上出现气管内插管套囊压力不足。26例患者(13.1%)在总麻醉时间的50%以下出现最佳气管内插管套囊压力。发现导致套囊压力不合适的因素各不相同,包括体位变化、手术操作、解剖操作和麻醉操作。

结论

在耳鼻咽喉科手术中,由于各种因素,套囊压力在适当范围之外升高或降低。因此,我们建议在耳鼻咽喉科手术麻醉期间密切持续监测套囊压力。

临床试验注册

clinicaltrials.gov,标识符NCT03938493。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc66/10277466/0e19d50d79d5/fmed-10-1161566-g001.jpg

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