Bhuiya Tanzim, Omeh Demian, Munshi Rezwan, Berookhim Brian, Roper Ashley, Vilcant Viliane, Syzdziak Elisa, Hai Ofek, Zeltser Roman, Digiacomo Jody, Makaryus Amgad N
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
Cardiology, Nassau University Medical Center, East Meadow, New York, USA.
Trauma Surg Acute Care Open. 2023 Jun 13;8(1):e001053. doi: 10.1136/tsaco-2022-001053. eCollection 2023.
The presence of permanent pacemakers (PPM) is common among the elderly population. Trauma literature has shown that the inability to augment cardiac output by at least 30% after injury portends a higher mortality. The presence of a PPM may be a surrogate marker to identify patients who are unable to increase cardiac output. We aimed to evaluate the association between the presence of PPM and clinical outcomes in elderly patients presenting with traumatic injuries.
A total of 4505 patients aged ≥65 years admitted with acute trauma from 2009 to 2019 at our Level I Trauma center were evaluated and stratified into two groups using propensity matching on age, sex, injury severity score (ISS), and year of admission based on the presence of PPM. Logistic regression was performed to analyze the impact of the presence of PPM on mortality, surgical intensive care unit (SICU) admission, operative intervention, and length of stay. Prevalence of cardiovascular comorbidities was compared using χ analysis.
Data from 208 patients with PPM and 208 propensity-matched controls were evaluated. Charlson Comorbidity Index, mechanism of injury, intensive care unit admission, and rate of operative intervention were comparable in the two groups. PPM patients had more coronary artery disease (p=0.04), heart failure with reduced ejection fraction (p=0.003), atrial fibrillation (AF, p<0.0001), and antithrombotic use (p<0.0001). We found no association between mortality amongst the groups after controlling for influencing variables (OR=2.1 (0.97 to 4.74), p=0.061). Patient characteristics associated with survival included female sex (p=0.009), lower ISS (p<0.0001), lower revised trauma score (p<0.0001), and lower SICU admission (p=0.001).
Our study shows no association between mortality among patients with PPM admitted for treatment of trauma. Presence of a PPM may be an indicator of cardiovascular disease, but this does not translate into increased risk in the modern era of trauma management in our patient population.
Level III.
永久性起搏器(PPM)在老年人群中很常见。创伤文献表明,受伤后心输出量至少无法增加30%预示着更高的死亡率。PPM的存在可能是识别那些无法增加心输出量患者的替代标志物。我们旨在评估PPM的存在与创伤老年患者临床结局之间的关联。
对2009年至2019年在我们的一级创伤中心因急性创伤入院的4505名年龄≥65岁的患者进行评估,并根据PPM的存在情况,基于年龄、性别、损伤严重程度评分(ISS)和入院年份进行倾向匹配,将患者分为两组。进行逻辑回归分析以评估PPM的存在对死亡率、外科重症监护病房(SICU)入院、手术干预和住院时间的影响。使用χ分析比较心血管合并症的患病率。
评估了208例有PPM患者和208例倾向匹配对照的数据。两组的Charlson合并症指数、损伤机制、重症监护病房入院率和手术干预率相当。有PPM的患者有更多的冠状动脉疾病(p=0.04)、射血分数降低的心力衰竭(p=0.003)、心房颤动(AF,p<0.0001)和抗栓治疗的使用(p<0.0001)。在控制影响变量后,我们发现两组之间的死亡率无关联(OR=2.1(0.97至4.74),p=0.061)。与生存相关的患者特征包括女性(p=0.009)、较低的ISS(p<0.0001)、较低的修订创伤评分(p<0.0001)和较低的SICU入院率(p=0.001)。
我们的研究表明,因创伤入院接受治疗的有PPM患者之间的死亡率无关联。PPM的存在可能是心血管疾病的一个指标,但在我们的患者群体中,在现代创伤管理时代,这并不会转化为更高的风险。
三级。