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在 11 家安全网急诊部门减少阿片类药物处方的日剂量。

Reducing daily dosing in opioid prescriptions in 11 safety net emergency departments.

机构信息

Icahn School of Medicine, New York, NY, USA; Department of Quality and Safety, NYC Health + Hospitals, New York, NY, USA.

Department of Quality and Safety, Brigham and Women's Hospital, Boston, MA, USA.

出版信息

Am J Emerg Med. 2023 Sep;71:63-68. doi: 10.1016/j.ajem.2023.06.005. Epub 2023 Jun 8.

Abstract

BACKGROUND

The United States continues to face a significant issue with opioid misuse, overprescribing, dependency, and overdose. Electronic health record (EHR) interventions have shown to be an effective tool to modify opioid prescribing behaviors. This quality improvement project describes an EHR intervention to reduce daily dosing in opioid prescriptions in 11 emergency departments (ED) across the largest safety net health system in the US.

MEASURES

The primary outcome measure was the rates of oxycodone-acetaminophen 5-325 mg prescriptions exceeding 50 morphine milligram equivalents per day (MMED) pre- vs. post-intervention; and stratified by individual hospitals and provider type.

INTERVENTION

The defaults for dose and frequency were uniformly changed to 'every 6 hours as needed' and '1 tablet', respectively, across 11 EDs.

OUTCOMES

The percentage of prescriptions greater than or equal to 50 MMED decreased from 46.0% (1624 of 3530 prescriptions) to 1.6% (52 of 3165 prescriptions) (96.4% relative reduction; p < 0.001). All 11 hospitals had a significant reduction in prescriptions exceeding 50 MMED. Nurse practitioners had the highest relative reduction of prescriptions exceeding 50 MMED at 100% (p < 0.001), and the attendings/fellows had the lowest relative reduction at 95.6% (p < 0.001).

CONCLUSIONS/LESSONS LEARNED: Default nudges are a simple yet powerful intervention that can strongly influence opioid prescribing patterns.

摘要

背景

美国仍然面临着阿片类药物滥用、过度处方、依赖和过量用药的重大问题。电子健康记录(EHR)干预已被证明是一种有效工具,可以改变阿片类药物的处方行为。本质量改进项目描述了一种 EHR 干预措施,以减少美国最大的医疗保障体系 11 个急诊部(ED)中阿片类药物处方的每日剂量。

措施

主要结果衡量标准是干预前后阿片类药物处方中羟考酮-对乙酰氨基酚 5-325mg 剂量超过 50 吗啡毫克当量/天(MMED)的比率;并按单个医院和提供者类型进行分层。

干预措施

在 11 个 ED 中,剂量和频率的默认值分别统一更改为“按需每 6 小时 1 片”和“1 片”。

结果

大于或等于 50 MMED 的处方百分比从 46.0%(1624 张处方中的 3530 张)降至 1.6%(3165 张处方中的 52 张)(相对减少 96.4%;p<0.001)。所有 11 家医院的处方都有显著减少。执业护士的处方减少率最高,达到 100%(p<0.001),主治医生/研究员的处方减少率最低,为 95.6%(p<0.001)。

结论/经验教训:默认提示是一种简单但强大的干预措施,可以强烈影响阿片类药物的处方模式。

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