Keeffe E B, Hisken E C, Schubert F
J Clin Gastroenterol. 1986 Jun;8(3 Pt 1):271-4. doi: 10.1097/00004836-198606000-00014.
A 40-year-old woman with chronic symptoms of gastroesophageal reflux had a 1.5-cm filling defect in the distal esophagus on esophagogram. Endoscopy revealed distal esophagitis and, immediately above a hiatal hernia, a pedunculated polyp on a short stalk, which was removed by snare cautery. The polyp was an adenoma composed of tubular glands and covered by intestinal-type epithelium. Serial distal esophageal biopsies confirmed Barrett's metaplasia with areas of specialized columnar epithelium with goblet cells. These findings suggest that the full expression of neoplasia in Barrett's esophagus includes the development of adenomatous polyps as well as dysplasia and adenocarcinoma.
一名患有慢性胃食管反流症状的40岁女性，食管造影显示食管远端有一个1.5厘米的充盈缺损。内镜检查发现食管远端食管炎，在食管裂孔疝上方紧邻处有一个带短蒂的有蒂息肉，通过圈套电灼术将其切除。该息肉是一个由管状腺体组成并被肠型上皮覆盖的腺瘤。连续的食管远端活检证实存在巴雷特化生，伴有含杯状细胞的特殊柱状上皮区域。这些发现表明，巴雷特食管肿瘤形成的完整表现包括腺瘤性息肉的发展以及发育异常和腺癌。
