Paraf F, Fléjou J F, Potet F, Molas G, Fékété F
Service d'Anatomie Pathologique, Hôpital Beaujon, Faculté de Médecine Xavier Bichat, Paris, France.
Pathol Res Pract. 1992 Dec;188(8):1028-32. doi: 10.1016/S0344-0338(11)81247-1.
Adenocarcinoma of the esophagus is a well known complication of Barrett's esophagus, and results from a dysplasia-carcinoma sequence. This report describes 3 patients with adenomatous polyps arising in Barrett's esophagus. One patient presented with multiple sessile or pedunculated polyps giving a polyposis appearance; the other two patients had single polyps associated with distinct adenocarcinoma arising in Barrett's esophagus. Polyps consisted of adenomatous proliferation with adenocarcinoma in the 3 patients. Review of the literature identified twelve previously reported cases. These cases show that although rare, adenomas may arise in Barrett's esophagus, and are most likely premalignant lesions such as other adenomas of the gastrointestinal tract.
食管腺癌是巴雷特食管一种广为人知的并发症，由发育异常-癌序列发展而来。本报告描述了3例在巴雷特食管中出现的腺瘤性息肉患者。1例患者表现为多个无蒂或有蒂息肉，呈现息肉病外观；另外2例患者有单个息肉，与巴雷特食管中出现的明确腺癌相关。3例患者的息肉均由腺瘤性增生伴腺癌组成。文献回顾发现了12例先前报道的病例。这些病例表明，尽管罕见，但腺瘤可能在巴雷特食管中出现，并且很可能是胃肠道其他腺瘤等癌前病变。
