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山楂多糖的结构特征、生物活性及产品应用研究进展。

Research progress on the structural characterization, biological activity and product application of polysaccharides from Crataegus pinnatifida.

机构信息

College of Chemistry and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Street, Shijiazhuang 050018, China.

College of Pharmacy, Hebei University of Chinese Medicine, 3 Xingyuan Road, Shijiazhuang 050200, China.

出版信息

Int J Biol Macromol. 2023 Jul 31;244:125408. doi: 10.1016/j.ijbiomac.2023.125408. Epub 2023 Jun 19.

Abstract

Crataegus pinnatifida is a plant of the Crataegus genus in the Rosaceae family and is commonly used as a food and medicinal resource. Crataegus pinnatifida polysaccharide, as one of the main active ingredients of Crataegus pinnatifida, has a variety of beneficial biological activities, such as antioxidant, hypoglycemic activity, lipid-lowering, intestinal flora regulation, promotion immune regulation, and antitumor activities. However, the extraction methods of Crataegus pinnatifida polysaccharides lack innovation, the primary structure is relatively limited, and the biological activity mechanism needs to be further explored. Therefore, this review summarizes the research status of the extraction, purification, structural characterization, biological activity, and product application of Crataegus pinnatifida polysaccharides. The purpose of this study is to generate support for further development and application of polysaccharides from Crataegus pinnatifida.

摘要

山茱萸是山茱萸属蔷薇科植物,通常被用作食物和药用资源。山茱萸多糖是山茱萸的主要活性成分之一,具有多种有益的生物活性,如抗氧化、降血糖、降血脂、调节肠道菌群、促进免疫调节、抗肿瘤等活性。然而,山茱萸多糖的提取方法缺乏创新,其一级结构相对有限,生物活性机制有待进一步探索。因此,本综述总结了山茱萸多糖的提取、纯化、结构表征、生物活性和产品应用的研究现状。本研究的目的是为进一步开发和应用山茱萸多糖提供支持。

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