van den Ende G M
J Infect. 1986 Jul;13(1):25-30. doi: 10.1016/s0163-4453(86)92164-x.
Over a period of 3 months during the summer, 362 African children admitted to King Edward VIII Hospital, Durban, were screened for the faecal excretion of Cryptosporidium oocysts. Of 259 children with diarrhoea, oocysts were detected in 31 (11.9%), while none was found in the faeces of 103 children without diarrhoea (controls). All those children excreting Cryptosporidium were under 2 years of age, giving a prevalence of 15% for this group. Other potential enteric pathogens were detected in the faeces of 12 (38.7%) of these children. The case fatality rate for patients with Cryptosporidium was 22.6%, which may reflect the selection of patients in a study concentrating on hospital inpatients. Cryptosporidium was the second most common organism detected in diarrhoeal faeces, and the only one detected in 9.2% of diarrhoeal children aged less than two years. These findings indicate that Cryptosporidium should be regarded as a potential pathogen in children admitted to this hospital with severe diarrhoea. Such association of Cryptosporidium with diarrhoea in children accords with recent studies in other parts of the world.
在夏季的3个月期间，对德班爱德华八世医院收治的362名非洲儿童进行了隐孢子虫卵囊粪便排泄情况筛查。259名腹泻儿童中，31名（11.9%）检测到卵囊，而103名无腹泻儿童（对照组）粪便中未发现卵囊。所有排出隐孢子虫的儿童均未满2岁，该组患病率为15%。这些儿童中有12名（38.7%）粪便中检测到其他潜在肠道病原体。隐孢子虫患者的病死率为22.6%，这可能反映了该研究集中于住院患者的患者选择情况。隐孢子虫是腹泻粪便中检测到的第二常见病原体，也是9.2%的2岁以下腹泻儿童中唯一检测到的病原体。这些发现表明，隐孢子虫应被视为该医院收治的严重腹泻儿童的潜在病原体。隐孢子虫与儿童腹泻的这种关联与世界其他地区最近的研究一致。
