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腹主动脉炎性动脉瘤的临床与治疗评估

Clinical and therapeutical evaluation of inflammatory aneurysms of the abdominal aorta.

作者信息

Fiorani P, Bondanini S, Faraglia V, Spartera C, Speziale F, Taurino M, Pistolese G R

出版信息

Int Angiol. 1986 Jan-Mar;5(1):49-53.

PMID:3734516
Abstract

Unexpected anatomical and clinical features of abdominal aortic aneurysm (AAA) may be encountered by the vascular surgeon creating technical problems that increase the normally low mortality rates of this affection. One such variant is the so called inflammatory aneurysm (IA) as a characteristic fibrosis involving the arterial wall and thus surrounding structure scan be observed. In our series of 525 patients affected by AAA the incidence of IA was about 4% (19 cases). Two groups of patients were considered: group A, including all the atherosclerotic patients, and group B 19 patients affected by IA. The latter group referred to a typical painful symptomatology in 84% of the cases: this element is of interest as only 20% of the cases of group A complained of pain. No other significant clinical or laboratory data were recorded which could allow the surgeon to perform a pre-operative differential diagnosis. In all 19 cases that underwent surgical treatment there was a 2-3 cm thick aneurysmal wall with a shiny white surface adhering to the IV portion of the duodenum, vena cava and iliac vessels and in some cases to the ureters. Histological examination of specimens of the aortic wall showed evident signs of atherosclerosis of the media and marked fibrotic thickening of the adventitia with the presence of lymphocyte aggregates: a sign of chronic inflammation. As what concerns indications and surgical treatment, there are no substantial differences. Pre-operative differential diagnosis can be made with CAT scan and ultrasound and the usual operative manoeuvres of aneurysmorrhaphy should be modified.

摘要

血管外科医生在处理腹主动脉瘤(AAA)时可能会遇到意外的解剖学和临床特征,这些特征会带来技术难题,从而增加这种疾病原本较低的死亡率。其中一种变异类型就是所谓的炎性动脉瘤(IA),其特征是动脉壁及周围结构出现纤维化。在我们收治的525例腹主动脉瘤患者中,炎性动脉瘤的发生率约为4%(19例)。我们将患者分为两组:A组为所有动脉粥样硬化患者,B组为19例炎性动脉瘤患者。后一组中84%的患者有典型的疼痛症状,这一点值得关注,因为A组中只有20%的患者主诉疼痛。未记录到其他显著的临床或实验室数据可帮助外科医生进行术前鉴别诊断。在接受手术治疗的所有19例患者中,动脉瘤壁厚2 - 3厘米,表面呈闪亮的白色,与十二指肠第四部分、腔静脉和髂血管粘连,在某些情况下还与输尿管粘连。主动脉壁标本的组织学检查显示,中膜有明显的动脉粥样硬化迹象,外膜有明显的纤维化增厚,并存在淋巴细胞聚集,这是慢性炎症的表现。关于手术指征和治疗方法,两者没有实质性差异。术前鉴别诊断可通过CT扫描和超声进行,动脉瘤缝合术的常规手术操作应做相应调整。

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