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Müller 胶质细胞到 Müller 胶质细胞细胞外囊泡依赖的信号转导诱导多能性基因的表达，并对 N-甲基-D-天冬氨酸（NMDA）暴露做出反应。

Müller Glia to Müller Glia Extracellular Vesicle-Dependent Signaling Induces Multipotency Genes and l Expression in Response to N-methyl-D-aspartate (NMDA) Exposure.

机构信息

Departamento de Farmacobiología, CINVESTAV, Ciudad de Mexico, México.

Centro de Investigacion sobre el envejecimiento, CINVESTAV, Ciudad de Mexico, México.

出版信息

ASN Neuro. 2023 Jan-Dec;15:17590914231183272. doi: 10.1177/17590914231183272.

DOI:10.1177/17590914231183272
PMID:37345290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10291543/
Abstract

Retinal Müller cells secrete extracellular vesicles that can be captured by other Müller cells. In response to a signal that may be deleterious for the retina, Müller glia-derived extracellular vesicles spread instructions to induce gene expression changes in other cells.

摘要

视网膜 Müller 细胞分泌细胞外囊泡，这些囊泡可以被其他 Müller 细胞捕获。在接收到可能对视网膜有害的信号后，Müller 胶质细胞衍生的细胞外囊泡传递指令，诱导其他细胞的基因表达变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/f7aeff59505a/10.1177_17590914231183272-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/520f43149c2a/10.1177_17590914231183272-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/3d0c294cad72/10.1177_17590914231183272-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/08110fa3a206/10.1177_17590914231183272-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/d4cd7bfac566/10.1177_17590914231183272-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/cfff17cda615/10.1177_17590914231183272-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/107a52f664c5/10.1177_17590914231183272-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/806151acd6f7/10.1177_17590914231183272-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/f7aeff59505a/10.1177_17590914231183272-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/520f43149c2a/10.1177_17590914231183272-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/3d0c294cad72/10.1177_17590914231183272-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/08110fa3a206/10.1177_17590914231183272-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/d4cd7bfac566/10.1177_17590914231183272-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/cfff17cda615/10.1177_17590914231183272-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/107a52f664c5/10.1177_17590914231183272-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/806151acd6f7/10.1177_17590914231183272-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0105/10291543/f7aeff59505a/10.1177_17590914231183272-fig8.jpg

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Alcohol Promotes Exosome Biogenesis and Release Modulating Rabs and miR-192 Expression in Human Hepatocytes.酒精促进外泌体生物发生和释放，调节人肝细胞中的Rabs和miR-192表达。
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