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多灶性单神经病作为血管内淋巴瘤的罕见表现：一例报告。

Mononeuropathy multiplex as an uncommon presentation of intravascular lymphoma: A case report.

作者信息

Haqi-Ashtiani Bahram, Moghaddam Parichehr, Barzkar Farzaneh, Zare Mehrjerdi Ali, Almasi-Dooghaee Mostafa

机构信息

Firoozgar Hospital, School of Medicine Iran University of Medical Sciences Tehran Iran.

Center for Educational Research in Medical Sciences(CERMS), School of Medicine Iran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2023 Jun 19;11(6):e7575. doi: 10.1002/ccr3.7575. eCollection 2023 Jun.

DOI:10.1002/ccr3.7575
PMID:37346885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10279939/
Abstract

KEY CLINICAL MESSAGE

Although intravascular lymphoma rarely presents with peripheral neuropathy, learning about this presentation can lead to timely diagnosis and improved prognosis in patients with intravascular lymphoma.

ABSTRACT

A 64-year-old man presented with asymmetric paresthesia and subsequent weakness of his feet and a 10 kg weight loss over 40 days. Electrodiagnostic studies revealed distal axonal sensory-motor polyneuropathy with ongoing axonal loss. A peroneal nerve biopsy showed intravascular proliferation of CD-20 positive lymphocytes, which suggested intravascular large B-cell lymphoma.

摘要

关键临床信息

尽管血管内淋巴瘤很少表现为周围神经病变，但了解这种表现可使血管内淋巴瘤患者得到及时诊断并改善预后。

摘要

一名64岁男性出现不对称性感觉异常，随后足部无力，40天内体重减轻10千克。电诊断研究显示为伴有持续性轴突丢失的远端轴索性感觉运动性多发性神经病。腓神经活检显示CD-20阳性淋巴细胞的血管内增殖，提示血管内大B细胞淋巴瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef32/10279939/ab8476e54ceb/CCR3-11-e7575-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef32/10279939/19b342112d29/CCR3-11-e7575-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef32/10279939/ab8476e54ceb/CCR3-11-e7575-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef32/10279939/19b342112d29/CCR3-11-e7575-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef32/10279939/ab8476e54ceb/CCR3-11-e7575-g002.jpg

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An update of neurological manifestations of vasculitides and connective tissue diseases: a literature review.血管炎和结缔组织病的神经学表现更新：文献综述
Einstein (Sao Paulo). 2015 Oct-Dec;13(4):627-35. doi: 10.1590/S1679-45082015RW3308. Epub 2015 Aug 21.
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