Department of Neurology, Jesse Brown VA Medical Center, Chicago, Illinois 60612, USA.
Muscle Nerve. 2010 Jul;42(1):133-6. doi: 10.1002/mus.21648.
We report a patient with intravascular large B-cell lymphoma who initially presented with acute ascending weakness and sensory changes. Electrodiagnostic testing and cerebral spinal fluid (CSF) studies were initially suggestive of a demyelinating polyneuropathy. Further clinical evaluation and testing were consistent with mononeuropathy multiplex. Autopsy revealed disseminated intravascular large-cell lymphoma. Intravascular large-cell lymphoma should be considered in the differential diagnosis of a rapidly evolving neuropathy associated with other organ involvement.
我们报告了一例初发表现为急性上升性无力和感觉改变的血管内大 B 细胞淋巴瘤患者。电诊断检查和脑脊液（CSF）研究最初提示脱髓鞘性多发性神经病。进一步的临床评估和检查与多发性单神经病一致。尸检显示弥漫性血管内大细胞淋巴瘤。血管内大细胞淋巴瘤在伴有其他器官受累的快速进展性神经病的鉴别诊断中应予以考虑。
