Department of Multidisciplinary Psychology, Kinjo Gakuin University, 2-1723 Omori, Moriyama-ku, Nagoya, Aichi, 463-8521, Japan.
Division of Psychology, Department of Cognitive and Psychological Sciences, Graduate School of Informatics, Nagoya University, Nagoya, Japan.
Cogn Affect Behav Neurosci. 2023 Aug;23(4):997-1013. doi: 10.3758/s13415-023-01087-3. Epub 2023 Jun 22.
People need to adapt to situations where they experience sequential benefits (or losses) to ensure survival. This study investigated the neural substrates involved in judgments of sequential benefits and losses. A total of 29 healthy volunteers participated in this study, in which they were asked to participate in a game of purchasing stocks while a magnetic resonance imaging scan was performed. This game had two main types of trials: (1) participants received four sequential financial benefits (or losses), and (2) participants received an equal amount of benefits (or losses) immediately. The results showed greater activation of the orbitofrontal cortex (OFC) when four benefits were received sequentially than when an equal amount of benefits was received immediately. This indicates that the OFC plays a crucial role in the process of mental integration of sequential benefits and interpretation of their valuations. It also showed greater activation of the dorsal striatum when four sequental losses were received than when an equal amount of losses was received immediately. However, it cannot be concluded that activation of the dorsal striatum reflects the differences between sequential and immediate losses, because previous studies have not confirmed this perspective. Therefore, it is necessary to clarify the function of the striatum in processing these losses.
人们需要适应连续获得（或损失）利益的情况，以确保生存。本研究调查了涉及连续获得和损失判断的神经基础。共有 29 名健康志愿者参与了这项研究，他们被要求在进行磁共振成像扫描的同时参与股票购买游戏。这个游戏有两种主要类型的试验：（1）参与者连续获得四次财务收益（或损失），（2）参与者立即获得等额的收益（或损失）。结果显示，当连续获得四次收益时，眶额皮层（OFC）的激活程度大于立即获得等额收益时。这表明 OFC 在连续收益的心理整合和解释其价值的过程中起着关键作用。当连续四次损失时，背侧纹状体的激活程度也大于立即获得等额损失时。然而，不能得出结论说背侧纹状体的激活反映了连续损失和即时损失之间的差异，因为之前的研究并没有证实这一观点。因此，有必要澄清纹状体在处理这些损失中的作用。
