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The interplay between bile acids and mucosal adaptive immunity.

作者信息

Mohammed Ahmed Dawood, Ball Ryan A W, Kubinak Jason L

机构信息

Department of Pathology, Microbiology, Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America.

出版信息

PLoS Pathog. 2023 Jun 22;19(6):e1011356. doi: 10.1371/journal.ppat.1011356. eCollection 2023 Jun.

DOI:10.1371/journal.ppat.1011356
PMID:37347728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10286976/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c3/10286976/2184cb2f9327/ppat.1011356.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c3/10286976/2184cb2f9327/ppat.1011356.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c3/10286976/2184cb2f9327/ppat.1011356.g001.jpg

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Mol Neurodegener. 2022 Jun 17;17(1):43. doi: 10.1186/s13024-022-00548-6.
2
Gluten-free diet exposure prohibits pathobiont expansion and gluten sensitive enteropathy in B cell deficient JH-/- mice.无麸质饮食可防止 B 细胞缺陷 JH-/- 小鼠中的条件致病菌扩张和麸质敏感肠病。
PLoS One. 2022 Mar 24;17(3):e0264977. doi: 10.1371/journal.pone.0264977. eCollection 2022.
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Human gut bacteria produce Τ17-modulating bile acid metabolites.
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Clin Transl Allergy. 2024 Feb;14(2):e12339. doi: 10.1002/clt2.12339.
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Gut microbiota-derived metabolites associate with circulating immune cell subsets in unexplained recurrent spontaneous abortion.肠道微生物群衍生的代谢产物与不明原因复发性自然流产中的循环免疫细胞亚群相关。
Heliyon. 2024 Jan 17;10(2):e24571. doi: 10.1016/j.heliyon.2024.e24571. eCollection 2024 Jan 30.
人体肠道细菌产生调节 T17 型细胞的胆汁酸代谢物。
Nature. 2022 Mar;603(7903):907-912. doi: 10.1038/s41586-022-04480-z. Epub 2022 Mar 16.
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Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory disease of the small bowel.体液免疫缺陷破坏胆汁酸稳态,从而促进小肠炎症性疾病。
Nat Commun. 2022 Jan 26;13(1):525. doi: 10.1038/s41467-022-28126-w.
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