Kram Yuri E, Sato Miori, Yamamoto-Hanada Kiwako, Toyokuni Kenji, Uematsu Satoko, Kudo Takahiro, Yamada Yoshiyuki, Ohtsuka Yoshikazu, Matsumoto Kenji, Arai Katsuhiro, Fukuie Tatsuki, Nomura Ichiro, Ohya Yukihiro
Allergy Center, National Center for Child Health and Development, Tokyo, Japan.
Division of Emergency and Transport Services, National Center for Child Health and Development, Tokyo, Japan.
World Allergy Organ J. 2023 May 9;16(5):100772. doi: 10.1016/j.waojou.2023.100772. eCollection 2023 May.
Reports of food protein-induced enterocolitis syndrome (FPIES) in Japan have been increasing. However, the disease itself and the treatment options are poorly understood by both patients and medical professionals. The objective of this study is to develop an action plan for acute FPIES in Japan. We prepared a single-sheet action plan that describes the management of acute FPIES episodes for caregivers on one side and medical professionals on the reverse side. To evaluate the content of the action plan, we distributed a questionnaire to caregivers of patients with FPIES and to physicians who would encounter patients with FPIES. Changes to the FPIES action plan were made based on the feedback from the participants. The Delphi method was utilized to finalize the action plan. The participants of the initial survey found the action plan to be useful but the process for determining severity to be impractical. After discussion, the authors made appropriate improvements. By the Delphi method, consensus was reached on the revised FPIES action plan. In conclusion, this Japanese FPIES action plan was created by physicians from multiple subspecialties and caregivers of patients with FPIES. The action plan may improve the management of acute FPIES reactions in the Japanese community.
日本关于食物蛋白诱导的小肠结肠炎综合征（FPIES）的报告一直在增加。然而，患者和医学专业人员对该疾病本身及其治疗方案的了解都很有限。本研究的目的是制定一份针对日本急性FPIES的行动计划。我们准备了一份单页行动计划，一面为护理人员描述急性FPIES发作的管理方法，另一面为医学专业人员提供相关内容。为了评估该行动计划的内容，我们向FPIES患者的护理人员以及可能接触FPIES患者的医生发放了问卷。根据参与者的反馈对FPIES行动计划进行了修改。采用德尔菲法确定最终的行动计划。初步调查的参与者认为该行动计划有用，但确定严重程度的过程不切实际。经过讨论，作者进行了适当改进。通过德尔菲法，就修订后的FPIES行动计划达成了共识。总之，这份日本FPIES行动计划是由多个亚专业的医生和FPIES患者的护理人员共同制定的。该行动计划可能会改善日本社区对急性FPIES反应的管理。
