• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肥大细胞缺陷小鼠(W/Wv)的着床、蜕膜瘤形成及活产情况

Implantation, deciduoma formation and live births in mast cell-deficient mice (W/Wv).

作者信息

Wordinger R J, Jackson F L, Morrill A

出版信息

J Reprod Fertil. 1986 Jul;77(2):471-6. doi: 10.1530/jrf.0.0770471.

DOI:10.1530/jrf.0.0770471
PMID:3735243
Abstract

The intraluminal injection of oil produced deciduoma formation in ovariectomized, mast cell-normal (+/+) and mast cell-deficient (W/Wv) mice that were treated with exogenous steroids. Oil injection and trauma (e.g. sutures) also produced a deciduoma in ovariectomized +/+ and W/Wv mice that had received a single control (+/+) ovary transplanted under the kidney capsule. After transfers of donor blastocysts, implantation and live births were obtained in +/+ and W/Wv mice containing a single ovary transplant. Our results demonstrate that uterine mast cells are not required for the production of a decidual cell response, implantation, gestation or the birth of live offspring in mice.

摘要

向经外源性类固醇处理的去卵巢、肥大细胞正常(+/+)和肥大细胞缺陷(W/Wv)小鼠的管腔内注射油可导致蜕膜瘤形成。对在肾被膜下移植了单个对照(+/+)卵巢的去卵巢+/+和W/Wv小鼠,注射油和造成创伤(如缝合)也会产生蜕膜瘤。在移植供体囊胚后,在含有单个卵巢移植物的+/+和W/Wv小鼠中实现了着床和活产。我们的结果表明,小鼠产生蜕膜细胞反应、着床、妊娠或活产后代并不需要子宫肥大细胞。

相似文献

1
Implantation, deciduoma formation and live births in mast cell-deficient mice (W/Wv).肥大细胞缺陷小鼠(W/Wv)的着床、蜕膜瘤形成及活产情况
J Reprod Fertil. 1986 Jul;77(2):471-6. doi: 10.1530/jrf.0.0770471.
2
An assessment of mast-cell deficient mice (W/Wv) as a model system to study the role of histamine in implantation and deciduoma formation.对肥大细胞缺陷小鼠(W/Wv)作为研究组胺在着床和蜕膜瘤形成中作用的模型系统的评估。
J Reprod Fertil. 1985 Mar;73(2):451-6. doi: 10.1530/jrf.0.0730451.
3
Deciduoma formation in uterus of genetically mast cell-deficient W/Wv mice.
Biol Reprod. 1982 Aug;27(1):25-8. doi: 10.1095/biolreprod27.1.25.
4
Cyclic AMP and the preparation of the mouse uterus for implantation.环磷酸腺苷与小鼠子宫着床准备
J Reprod Fertil. 1977 May;50(1):83-9. doi: 10.1530/jrf.0.0500083.
5
Studies using the estrogen receptor alpha knockout uterus demonstrate that implantation but not decidualization-associated signaling is estrogen dependent.使用雌激素受体α基因敲除子宫的研究表明,着床而非蜕膜化相关信号传导是雌激素依赖性的。
Biol Reprod. 2002 Oct;67(4):1268-77. doi: 10.1095/biolreprod67.4.1268.
6
REACTION OF THE MOUSE UTERUS DURING IMPLANTATION AND DECIDUOMA FORMATION AS DEMONSTRATED BY CHANGES IN THE DISTRIBUTION OF ALKALINE PHOSPHATASE.碱性磷酸酶分布变化所显示的小鼠子宫在着床和蜕膜瘤形成过程中的反应
J Reprod Fertil. 1964 Dec;8:331-8. doi: 10.1530/jrf.0.0080331.
7
A pathogenetic role for mast cells in experimental crescentic glomerulonephritis.肥大细胞在实验性新月体性肾小球肾炎中的发病机制作用。
J Am Soc Nephrol. 2006 Jan;17(1):150-9. doi: 10.1681/ASN.2005080799. Epub 2005 Nov 30.
8
Mast-cell-deficient W/Wv mice exhibit a decreased rate of tumor angiogenesis.肥大细胞缺陷的W/Wv小鼠表现出肿瘤血管生成速率降低。
Int J Cancer. 1988 Jul 15;42(1):48-52. doi: 10.1002/ijc.2910420110.
9
PAF-induced airways hyperreactivity is modulated by mast cells in mice.血小板活化因子诱导的气道高反应性受小鼠肥大细胞调节。
Am J Respir Cell Mol Biol. 1996 May;14(5):461-9. doi: 10.1165/ajrcmb.14.5.8624251.
10
Mast cells modulate acute ozone-induced inflammation of the murine lung.肥大细胞调节急性臭氧诱导的小鼠肺部炎症。
Am Rev Respir Dis. 1993 Nov;148(5):1284-91. doi: 10.1164/ajrccm/148.5.1284.

引用本文的文献

1
Killer Immunoglobulin-Like Receptor 2DL4 (CD158d) Regulates Human Mast Cells both Positively and Negatively: Possible Roles in Pregnancy and Cancer Metastasis.杀伤细胞免疫球蛋白样受体 2DL4(CD158d)正性和负性调节人肥大细胞:在妊娠和癌症转移中的可能作用。
Int J Mol Sci. 2020 Jan 31;21(3):954. doi: 10.3390/ijms21030954.
2
Human Chorionic Gonadotropin-Mediated Immune Responses That Facilitate Embryo Implantation and Placentation.人绒毛膜促性腺激素介导的免疫反应促进胚胎着床和胎盘形成。
Front Immunol. 2019 Dec 10;10:2896. doi: 10.3389/fimmu.2019.02896. eCollection 2019.
3
Mast cells as novel mediators of reproductive processes.
肥大细胞作为生殖过程的新型介质。
Front Immunol. 2013 Feb 14;4:29. doi: 10.3389/fimmu.2013.00029. eCollection 2013.
4
The hamster as a model for embryo implantation: insights into a multifaceted process.仓鼠作为胚胎植入模型:对一个多方面过程的见解。
Semin Cell Dev Biol. 2008 Apr;19(2):194-203. doi: 10.1016/j.semcdb.2007.11.001. Epub 2007 Dec 4.
5
Distribution patterns of immunocompetent cells in the pregnant mouse uteri carrying allogeneic mouse and xenogeneic vole embryos.携带同种异体小鼠胚胎和异种田鼠胚胎的妊娠小鼠子宫中免疫活性细胞的分布模式
J Anat. 2004 Jul;205(1):45-55. doi: 10.1111/j.0021-8782.2004.00314.x.
6
Uterine decidual response occurs in estrogen receptor-alpha-deficient mice.雌激素受体α缺陷小鼠会出现子宫蜕膜反应。
Endocrinology. 1999 Jun;140(6):2704-10. doi: 10.1210/endo.140.6.6825.