Shanghai Aier Eye Hospital, Shanghai Aier Eye Institute, Shanghai, China.
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
BMC Ophthalmol. 2023 Jun 23;23(1):287. doi: 10.1186/s12886-023-03047-4.
To assess the anxiety and depression levels in patients with Posner-Schlossman syndrome (PSS) and to determine the potential risk factors.
In this cross-sectional study, a total of 195 participants, including 93 PSS patients and 102 healthy controls were recruited. Sociodemographic and clinical information were collected for all participants. Hospital Anxiety and Depression scale (HADS) was administered to evaluate the anxiety and depression levels. Visual function (VF) and quality-of-life (QOL) questionnaires were administered to assess variables potentially associated with anxiety and depression.
Increased anxiety level was observed in 22 (23.7%) PSS patients as compared to 10 (9.8%) of controls (P = 0.009). While the frequency of depression between the two groups was not significantly different (P = 0.349). The mean anxiety and depression scores were 6.98 ± 4.20 and 6.44 ± 3.66 in PSS patients as compared to 6.67 ± 3.21 (P = 0.564) and 5.96 ± 2.93 (P = 0.311) in controls. Logistic regression analysis showed mental well-being was significantly associated with anxiety (odds ratio [OR] = 0.920, 95% confidence interval [CI] = 0.881-0.962, P < 0.001) and depression (OR = 0.959, CI = 0.926-0.994, P = 0.023) in PSS patients.
More patients with PSS may experience anxiety as compared to healthy controls. Mental well-being is an independent risk factor for anxiety and depression. It is important for ophthalmologists to be aware of these factors and should pay more attention on mental health when PSS is managed in clinic.
评估 Posner-Schlossman 综合征（PSS）患者的焦虑和抑郁水平，并确定潜在的危险因素。
在这项横断面研究中，共招募了 195 名参与者，包括 93 名 PSS 患者和 102 名健康对照者。收集所有参与者的社会人口学和临床信息。采用医院焦虑抑郁量表（HADS）评估焦虑和抑郁水平。采用视觉功能（VF）和生活质量（QOL）问卷评估可能与焦虑和抑郁相关的变量。
与 10 名健康对照组（9.8%）相比，22 名（23.7%）PSS 患者存在焦虑水平升高（P=0.009）。然而，两组之间的抑郁发生率差异无统计学意义（P=0.349）。PSS 患者的平均焦虑和抑郁评分分别为 6.98±4.20 和 6.44±3.66，而健康对照组的平均焦虑和抑郁评分分别为 6.67±3.21（P=0.564）和 5.96±2.93（P=0.311）。Logistic 回归分析显示，心理健康与 PSS 患者的焦虑（比值比[OR] = 0.920，95%置信区间[CI] = 0.881-0.962，P<0.001）和抑郁（OR = 0.959，CI = 0.926-0.994，P=0.023）显著相关。
与健康对照组相比，更多的 PSS 患者可能会出现焦虑。心理健康是焦虑和抑郁的独立危险因素。眼科医生应该意识到这些因素，在临床管理 PSS 时应更加关注心理健康。
