Ondokuz Mayıs University Faculty of Medicine, Department of Ophtalmology, Samsun, Turkey.
Ondokuz Mayıs University Faculty of Medicine, Department of Mental Health, Samsun, Turkey.
Turk J Ophthalmol. 2021 Dec 28;51(6):358-364. doi: 10.4274/tjo.galenos.2020.06791.
To evaluate the effect of vision-related quality of life on depression and anxiety in patients with Behçet uveitis.
The Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI) I-II, and the Visual Functioning Questionnaire (VFQ)-25 were used to evaluate 105 patients being followed for Behçet uveitis. Sociodemographic data and VFQ-25 scores were compared between the groups with and without depression and anxiety. Regression analysis was performed to determine the relationship between the variables.
Forty-eight (82.8%) men and 10 (17.2%) women who completed the questionnaires were included in the study. The mean age of the patients was 37.76±11.14 (18-65) years and the mean duration of uveitis was 8.57±7.43 (1-27) years. The mean VFQ-25 composite, BDI, STAI-I, and STAI-II scores were 74.90±18.50 (18.79-97.04), 10.76±8.90 (0-43), 42.52±6.23 (25-55), and 46.53±6.80 (27-58), respectively. Of 58 patients, 31% had depressive symptoms and 58.6% had anxiety symptoms. VFQ-25 composite score was lower in the depressive group than in the group with no depression (p=0.030), while there was no significant difference in this score between the groups with and without anxiety. Regression analysis revealed a negative relationship between total VFQ-25 composite score and depression.
In our study, high rates of depression and anxiety were detected in patients with Behçet uveitis. Patient-reported visual functioning was associated with depression. In patients with Behçet uveitis, it is important to evaluate vision-related quality of life as well as visual acuity.
评估与视觉相关的生活质量对 Behcet 葡萄膜炎患者抑郁和焦虑的影响。
使用贝克抑郁量表（BDI）、状态特质焦虑量表（STAI）I-II 以及视功能问卷（VFQ）-25 评估 105 例 Behcet 葡萄膜炎患者。比较有和无抑郁和焦虑患者的社会人口统计学数据和 VFQ-25 评分。进行回归分析以确定变量之间的关系。
本研究纳入了 48 名（82.8%）男性和 10 名（17.2%）女性完成了问卷调查的患者。患者的平均年龄为 37.76±11.14 岁（18-65 岁），葡萄膜炎的平均病程为 8.57±7.43 年（1-27 年）。VFQ-25 综合评分、BDI、STAI-I 和 STAI-II 的平均值分别为 74.90±18.50（18.79-97.04）、10.76±8.90（0-43）、42.52±6.23（25-55）和 46.53±6.80（27-58）。在 58 名患者中，31%有抑郁症状，58.6%有焦虑症状。与无抑郁组相比，抑郁组的 VFQ-25 综合评分较低（p=0.030），而焦虑组与无焦虑组之间的评分无显著差异。回归分析显示，VFQ-25 综合评分与抑郁呈负相关。
在本研究中，我们发现 Behcet 葡萄膜炎患者中存在较高的抑郁和焦虑发生率。患者报告的视觉功能与抑郁相关。在 Behcet 葡萄膜炎患者中，评估与视觉相关的生活质量以及视力非常重要。
