Department of Population Health, University of Otago, Christchurch, New Zealand.
Department of Psychological Medicine, University of Otago, Christchurch, New Zealand.
J Psychopharmacol. 2023 Sep;37(9):891-903. doi: 10.1177/02698811231182012. Epub 2023 Jun 23.
The harms arising from psychoactive drug use are complex, and harm reduction strategies should be informed by a detailed understanding of the extent and nature of that harm. Drug harm is also context specific, and so any comprehensive assessment of drug harm should be relevant to the characteristics of the population in question. This study aimed to evaluate and rank drug harms within Aotearoa New Zealand using a multi-criteria decision analysis (MCDA) framework, and to separately consider harm within the total population, and among youth.
Two facilitated workshops involved the separate ranking of harm for the total population, and then for youth aged 12-17, by two expert panels. In the total population workshop, 23 drugs were scored against 17 harm criteria, and those criteria were then evaluated using a swing weighting process. Scoring and weighting were subsequently updated during the youth-specific workshop. All results were recorded and analysed using specialised MCDA software.
When considering overall harm, the MCDA modelling results indicated that alcohol, methamphetamine and synthetic cannabinoids were the most harmful to both the overall population and the youth, followed by tobacco in the total population. Alcohol remained the most harmful drug for the total population when separately considering harm to those who use it, and harm to others.
The results provide detailed and context-specific insight into the harm associated with psychoactive drugs use within Aotearoa New Zealand. The findings also demonstrate the value of separately considering harm for different countries, and for different population subgroups.
精神活性药物使用带来的危害是复杂的,减少危害的策略应该基于对这种危害的程度和性质的深入了解。药物危害也是特定于情境的,因此对药物危害的任何全面评估都应该与所涉及人群的特征相关。本研究旨在使用多准则决策分析(MCDA)框架评估和排名新西兰的药物危害,并分别考虑整个人群和年轻人中的危害。
两个专题研讨会分别由两个专家小组对整个人群和 12-17 岁的年轻人的危害进行排名。在整个人群研讨会上,23 种药物根据 17 项危害标准进行评分,然后使用摇摆权重过程对这些标准进行评估。在青年专题研讨会上对评分和权重进行了更新。所有结果均使用专门的 MCDA 软件进行记录和分析。
当考虑总体危害时,MCDA 模型结果表明,酒精、甲基苯丙胺和合成大麻素对整个人群和年轻人的危害最大,其次是整个人群中的烟草。当单独考虑那些使用酒精的人的危害和对他人的危害时,酒精仍然是整个人群中最有害的药物。
这些结果提供了关于新西兰精神活性药物使用相关危害的详细和特定于情境的见解。研究结果还表明,分别考虑不同国家和不同人群亚组的危害具有价值。