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利用基于污水的流行病学方法,在与人口普查时间同步的情况下,评估新西兰非法药物使用的时空和社会经济模式。

Spatial, temporal and socioeconomic patterns of illicit drug use in New Zealand assessed using wastewater-based epidemiology timed to coincide with the census.

机构信息

School of Environment, University of Auckland, Auckland.

Drug Research Team Leader, SHORE & Whariki Research Centre, College of Health, Massey University.

出版信息

N Z Med J. 2021 Jun 25;134(1537):11-26.

Abstract

AIMS

A discrete experiment in wastewater-based epidemiology (WBE) timed to coincide with the census was used to investigate the spatial, temporal and socioeconomic patterns of illicit drug consumption in Auckland, Bay of Plenty and Canterbury.

METHODS

For seven consecutive days over census week (6 March 2018), wastewater was sampled from seven wastewater treatment plants and analysed for methamphetamine, cocaine (as benzoylecgonine) and 3,4-methylenedioxymethamphetamine (MDMA). Detailed sewer catchment maps were developed and, together with the data, were used to analyse drug consumption.

RESULTS

Methamphetamine (mean 22.9 ± 9.9 doses/day/1000 people) was the most consumed drug, followed by MDMA (mean 1.7 ± 1.5 doses/day/1000 people) and cocaine (mean 0.5 ± 0.3 doses/day/1000 people). Methamphetamine consumption (and to a lesser extent MDMA) was high compared to that reported for Western nations, while cocaine consumption was extremely low. Cocaine and MDMA consumption were higher in cities compared to towns. In contrast, methamphetamine was typically higher in towns. Cocaine and MDMA were consumed more at weekends. Methamphetamine use was more consistent throughout the week. MDMA and cocaine were correlated with socioeconomic advantage, whereas methamphetamine was correlated with disadvantage.

CONCLUSIONS

This paper contextualises illicit drug use in three New Zealand regions containing 18.3% of the national population and confirms the pervasiveness of methamphetamine consumption in New Zealand towns. This work demonstrates how WBE can be used to explore the socioeconomic dimensions of drug use when duly combined with other data sources like censuses.

摘要

目的

利用与人口普查时间同步的基于废水的流行病学(WBE)离散实验,调查奥克兰、丰盛湾和坎特伯雷非法药物消费的空间、时间和社会经济模式。

方法

在人口普查周(2018 年 3 月 6 日)的连续七天内,从七个污水处理厂采集废水,并分析其中的甲基苯丙胺、可卡因(苯甲酰可卡因)和 3,4-亚甲二氧基甲基苯丙胺(MDMA)。开发了详细的污水管网集水区地图,并与数据一起用于分析药物消费。

结果

甲基苯丙胺(平均 22.9 ± 9.9 剂量/天/1000 人)是消费最多的药物,其次是 MDMA(平均 1.7 ± 1.5 剂量/天/1000 人)和可卡因(平均 0.5 ± 0.3 剂量/天/1000 人)。与西方国家报告的情况相比,甲基苯丙胺(在较小程度上还有 MDMA)的消费较高,而可卡因的消费极低。与城镇相比,可卡因和 MDMA 的消费在城市更高。相反,甲基苯丙胺通常在城镇更高。可卡因和 MDMA 在周末消费更多。甲基苯丙胺的使用在一周内更为一致。MDMA 和可卡因与社会经济优势相关,而甲基苯丙胺与劣势相关。

结论

本文在包含全国 18.3%人口的三个新西兰地区背景下对非法药物使用进行了说明,并证实了甲基苯丙胺在新西兰城镇中的普遍存在。这项工作展示了如何在与其他数据源(如人口普查)适当结合的情况下,利用 WBE 来探索药物使用的社会经济维度。

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