Ministry of Education (MOE) Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou 510006, PR China.
Ministry of Education (MOE) Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou 510006, PR China.
Food Chem. 2023 Nov 15;426:136626. doi: 10.1016/j.foodchem.2023.136626. Epub 2023 Jun 15.
The wide use and high polarity of nitrobenzene compounds (NBCs) have caused a concern for their residues in daily beverages. Herein, the covalent organic frameworks (COFs) with abundant carboxyl were ingeniously designed by introducing a novel modulator, and further developed as solid phase microextraction (SPME) coatings. Due to the enhanced polar interaction, the extraction efficiencies of modified COF for NBCs were sharply increased. After coupling the high-performance SPME fiber with gas chromatograph-mass spectrometry (GC-MS), an ultrasensitive analytical method was developed, with a wide linear range (0.50-5000 ng/L), and low limits of detection (0.15-3.0 ng/L). More importantly, the method was highly feasible and practical, leading to the precise determinations of trace NBCs from variously matrix-complicated samples. This work provides a viable and efficacious approach for the extraction and analysis of polar pollutants form complicated matrices, and is of great significance for mild COF modification and its extended applications in analytical chemistry.
硝基苯化合物（NBCs）的广泛使用和高极性引起了人们对其在日常饮料中残留的关注。在此，通过引入一种新型调节剂，巧妙地设计了具有丰富羧基的共价有机框架（COFs），并进一步开发为固相微萃取（SPME）涂层。由于增强的极性相互作用，修饰后的 COF 对 NBCs 的萃取效率大大提高。将高性能 SPME 纤维与气相色谱-质谱联用（GC-MS）耦合后，开发了一种超灵敏的分析方法，具有较宽的线性范围（0.50-5000ng/L）和较低的检测限（0.15-3.0ng/L）。更重要的是，该方法具有很高的可行性和实用性，可实现从各种基质复杂的样品中精确测定痕量 NBCs。这项工作为从复杂基质中提取和分析极性污染物提供了一种可行且有效的方法，对于温和的 COF 修饰及其在分析化学中的扩展应用具有重要意义。
