高龄（35岁及以上）与低龄妊娠创伤患者的结局：一项多中心研究。
Outcomes for advanced aged (35 and older) versus younger aged pregnant trauma patients: A multicenter study.
作者信息
Aryan Negaar, Grigorian Areg, Lucas Alexa N, Tay-Lasso Erika, Zezoff Danielle C, Fierro Nicole, Dhillon Navpreet K, Ley Eric J, Smith Jennifer, Dahan Alden, Johnson Arianne, Ganske William, Biffl Walter L, Bayat Dunya, Castelo Matthew, Wintz Diane, Schaffer Kathryn B, Zheng Dennis J, Tillou Areti, Coimbra Raul, Santorelli Jarrett E, Schellenberg Morgan, Inaba Kenji, Emigh Brent, Duncan Thomas K, Diaz Graal, Burruss Sigrid, Tuli Rahul, Nahmias Jeffry
机构信息
University of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, Orange, California, USA.
Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
出版信息
Am J Surg. 2023 Dec;226(6):798-802. doi: 10.1016/j.amjsurg.2023.06.004. Epub 2023 Jun 2.
BACKGROUND
Effects of advanced maternal age (AMA) pregnancies (defined as ≥35 years) on pregnant trauma patients (PTPs) are unknown. This study compared AMA versus younger PTPs, hypothesizing AMA PTPs have increased risk of fetal delivery (FD).
METHODS
A retrospective (2016-2021) multicenter study included all PTPs. Multivariable logistic regression was used to evaluate risk of FD after trauma.
RESULTS
A total of 950 PTPs were included. Both cohorts had similar gestational age and injury severity scores. The AMA group had increased injuries to the pancreas, bladder, and stomach (p < 0.05). There was no difference in rate or associated risk of FD between cohorts (5.3% vs. 11.4%; OR 0.59, CI 0.19-1.88, p > 0.05).
CONCLUSION
Compared to their younger counterparts, some intra-abdominal injuries (pancreas, bladder, and stomach) were more common among AMA PTPs. However, there was no difference in rate or associated risk of FD in AMA PTPs, thus they do not require increased observation.
背景
高龄孕产妇（定义为年龄≥35岁）妊娠对创伤孕妇的影响尚不清楚。本研究比较了高龄孕产妇与年轻创伤孕妇，假设高龄孕产妇发生胎儿娩出（FD）的风险增加。
方法
一项回顾性（2016 - 2021年）多中心研究纳入了所有创伤孕妇。采用多变量逻辑回归评估创伤后胎儿娩出的风险。
结果
共纳入950例创伤孕妇。两组的孕周和损伤严重程度评分相似。高龄孕产妇组胰腺、膀胱和胃部的损伤增加（p < 0.05）。两组之间胎儿娩出的发生率或相关风险无差异（5.3%对11.4%；比值比0.59，可信区间0.19 - 1.88，p > 0.05）。
结论
与年轻创伤孕妇相比，高龄孕产妇创伤孕妇中一些腹腔内损伤（胰腺、膀胱和胃部）更为常见。然而，高龄孕产妇创伤孕妇胎儿娩出的发生率或相关风险无差异，因此不需要增加观察。
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