From the Department of Obstetrics and Gynecology, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
From the College of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Ann Saudi Med. 2021 Sep-Oct;41(5):274-279. doi: 10.5144/0256-4947.2021.274. Epub 2021 Oct 7.
Pregnancy in women aged 35 years or above is generally considered an advanced maternal age (AMA). AMA is associated with an increased rate of maternal and neonatal complications.
Assess the effect of AMA on maternal and neonatal outcomes.
Analytical cross-sectional study of medical records.
In-patient hospital tertiary care setting in Jeddah.
All women who attended antenatal care and delivered at King Abdulaziz Medical City in Jeddah in the first half of 2018 were included in the study. Outcomes for women 35 years of age or older were compared with younger women. Significant factors in a univariate analysis were entered in a multiple logistic regression model to assess the association between AMA and outcomes.
Rates of maternal neonatal complications, analysis of factors associated with advanced maternal, gestational diabetes mellitus (GDM), cesarean delivery.
1586 women.
Of the 1586 women, 406 were 35 years of age or older (25.6%), and 1180 were younger than 35 years. The AMA group had a significantly higher proportion of GDM (32.0% versus 13.2%, <.001). The adjusted odds ratio (OR) for GDM was 2.6 (95% CI 2-3.5, <.001.) compared with younger women in the multivariate logistic regression analysis. Older women had a higher rate of cesarean delivery (43.6% versus 30.8%, <.001). The adjusted OR for cesarean vs. vaginal delivery was 1.5 (CI 1.2-1.9, =.002).
Pregnancy in women 35 years or older was associated with an increased risk of GDM and cesarean delivery.
Cross-sectional design, small sample size, single hospital.
None.
35 岁及以上的女性妊娠通常被认为是高龄产妇（AMA）。AMA 与产妇和新生儿并发症的发生率增加有关。
评估 AMA 对母婴结局的影响。
对病历进行分析性横断面研究。
吉达阿卜杜勒阿齐兹国王医疗城的住院三级保健机构。
所有在 2018 年上半年在吉达阿卜杜勒阿齐兹国王医疗城接受产前护理并分娩的女性均纳入本研究。将 35 岁及以上女性的结局与年轻女性进行比较。单因素分析中的显著因素被纳入多因素逻辑回归模型，以评估 AMA 与结局之间的关系。
母婴并发症发生率，分析与高龄产妇相关的因素、妊娠期糖尿病（GDM）、剖宫产。
1586 名女性。
在 1586 名女性中，406 名年龄在 35 岁及以上（25.6%），1180 名年龄小于 35 岁。AMA 组 GDM 比例明显较高（32.0%比 13.2%，<0.001）。在多因素逻辑回归分析中，与年轻女性相比，GDM 的调整比值比（OR）为 2.6（95%CI 2-3.5，<0.001）。年龄较大的女性剖宫产率较高（43.6%比 30.8%，<0.001）。剖宫产与阴道分娩的调整 OR 为 1.5（CI 1.2-1.9，=0.002）。
35 岁及以上女性妊娠与 GDM 和剖宫产风险增加相关。
横断面设计、样本量小、单家医院。
无。
