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颈动脉内膜切除术联合眼体积描记法的生理学研究

Physiology of carotid endarterectomy with ocular pneumoplethysmography.

作者信息

Gee W, Perline R K, Madden A E

出版信息

J Vasc Surg. 1986 Aug;4(2):129-35. doi: 10.1067/mva.1986.avs0040129.

Abstract

Objective documentation of the quantitative physiologic changes associated with the repair of carotid lesions of hemodynamic consequence was obtained in 701 procedures by a comparison of pre- and postoperative ocular pneumoplethysmographic tests (OPG-Gee). The results of repair of severe stenoses depended on the status of the carotid artery opposite the repaired vessel. If the vessel opposite the carotid artery repaired was functionally patent, severely stenosed, or totally occluded, the ocular blood flow improvement on the side of repair was 16%, 27%, and 47%, respectively. Only in the latter group was improvement in ocular blood flow observed on the side opposite the carotid repair (13%). Ocular blood flow, the bulk of which (choroid) is not autoregulated, is a much more sensitive indicator of carotid lesions of hemodynamic consequence than is the autoregulated cerebral blood flow. OPG-Gee is presented as a simple noninvasive test that reliably and reproducibly assesses the quantitative physiologic changes associated with the repair of carotid lesions of hemodynamic consequence. The latter represent 84% of all carotid endarterectomies at this institution.

摘要

通过比较术前和术后的眼体积描记图测试(OPG-Gee),对701例具有血流动力学影响的颈动脉病变修复相关的定量生理变化进行了客观记录。严重狭窄修复的结果取决于修复血管对侧颈动脉的状态。如果修复的颈动脉对侧血管功能正常、严重狭窄或完全闭塞,修复侧的眼血流量改善分别为16%、27%和47%。仅在后一组中,在颈动脉修复对侧观察到眼血流量改善(13%)。大部分(脉络膜)不受自身调节的眼血流量,是比自身调节的脑血流量更敏感的具有血流动力学影响的颈动脉病变指标。OPG-Gee作为一种简单的非侵入性测试方法被提出,它能可靠且可重复地评估与具有血流动力学影响的颈动脉病变修复相关的定量生理变化。后者占该机构所有颈动脉内膜切除术的84%。

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