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口腔鳞状细胞癌早期治疗的重要性:病例报告。

The importance of early treatment of oral squamous cell carcinoma: Case report.

机构信息

Oral Semiology and Oral Pathology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.

Oral Semiology and Oral Pathology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.

出版信息

Oral Oncol. 2023 Sep;144:106442. doi: 10.1016/j.oraloncology.2023.106442. Epub 2023 Jun 23.

Abstract

BACKGROUND

Oral squamous cell carcinoma (OSCC) is frequently diagnosed at an advanced stage, with the five-year survival rate varying around 50%, however, ifs the sooner OSCC in early-stage is treated, the lower the chances of recurrence and death. In this study, we described an OSCC diagnosed early, highlighting how the early surgical excision prevents the morbidity.

CASE REPORT

A 74-year-old man presented a whitish and symptomatic plaque and a discreet ulcerated area on the right lateral border of the tongue. Due to close contact with the second inferior molar, a clinical diagnosis of a frictional keratosis was suspected, however as the lesion persisted after two weeks of follow-up, an incisional biopsy was performed and the microscopic features revealed an OSCC. Early surgical resection was performed, preventing the morbidity and improve benefits to patient.

CONCLUSION

OSCC can manifest of several clinical forms, including indolent appearances, which can delay the diagnosis, and consequently the prognosis. Further, it is important to recognize and not neglect any intraoral lesions, in order to avoid the far more invasive surgery that a more advance disease would imply.

摘要

背景

口腔鳞状细胞癌(OSCC)常被诊断为晚期,五年生存率约为 50%,然而,如果能及早治疗早期 OSCC,复发和死亡的几率就越低。本研究描述了一例早期诊断的 OSCC,强调了早期手术切除可预防发病。

病例报告

一名 74 岁男性舌右侧外侧缘出现白色症状性斑块和一处轻微溃疡性区域。由于与第二下磨牙紧密接触,临床诊断为摩擦性角化病,但在两周的随访后,病变仍未消退,于是进行了切开活检,显微镜下特征显示为 OSCC。早期手术切除,预防了发病和改善了患者的预后。

结论

OSCC 可表现为多种临床形式,包括惰性表现,这可能会延迟诊断,进而影响预后。此外,重要的是要认识到并不能忽视任何口腔内的病变,以避免更严重的侵袭性手术,这对于更晚期的疾病来说是不可避免的。

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