Nursing Department, Affiliated Hospital of Zunyi Medical University, 563000, ZunYi, Guizhou, China.
Nursing College, ZunYi Medical University, 563000, ZunYi, Guizhou, China.
BMC Endocr Disord. 2023 Jun 25;23(1):135. doi: 10.1186/s12902-023-01385-4.
Using latent class to analyze whether there are subtypes of health behaviors in patients with PCOS can be addressed using targeted interventions.
October 2021 to June 2022, 471 PCOS patients were surveyed using the Health Promoting Lifestyle Profile Questionnaire. Latent class analysis (LCA) was used to identify subgroups of PCOS patients. Subsequent multinomial latent variable regressions identified factors that were associated with health behaviors.
A three-class subtypes was the optimum grouping classification: (1)High healthy behavior risk; (2)high healthy responsibility and physical activity risk; (3)low healthy behavior risk. The multinomial logistic regression analysis revealed that (1)Single (OR = 2.061,95% CI = 1.207-3.659), Education level is primary school or below (OR = 4.997,95%CI = 1.732-14.416), participants is student (OR = 0.362,95%=0.138-0.948), participants with pregnancy needs (OR = 1.869,95%=1.009-3.463) were significantly more likely to be in the high healthy behavior risk subtypes; (2)The older the age (OR = 0.953,95%=0.867-1.047) and the larger the WC (OR = 0.954,95%=0.916-0.993), participants is married (OR = 1.126,95%=0.725-1.961), participants is employed ( OR = 1.418,95%=0.667-3.012) were significantly more likely to be in the high health responsibility and physical activity risk subtypes.
Patients with PCOS are a heterogeneous population with potential subtypes that may be suitable for customized multi-level care and targeted interventions.
通过潜在类别分析(LCA),探讨多囊卵巢综合征(PCOS)患者的健康行为是否存在亚类,以便采用针对性干预措施。
2021 年 10 月至 2022 年 6 月,采用健康促进生活方式量表对 471 例 PCOS 患者进行调查。采用潜在类别分析(LCA)识别 PCOS 患者亚组。随后采用多项潜在变量回归分析确定与健康行为相关的因素。
三组亚类是最佳分组分类:(1)高健康行为风险;(2)高健康责任和体力活动风险;(3)低健康行为风险。多分类逻辑回归分析显示:(1)单身(OR=2.061,95%CI=1.207-3.659)、教育水平为小学及以下(OR=4.997,95%CI=1.732-14.416)、学生(OR=0.362,95%CI=0.138-0.948)、有妊娠需求(OR=1.869,95%CI=1.009-3.463)的参与者更有可能属于高健康行为风险亚组;(2)年龄越大(OR=0.953,95%CI=0.867-1.047)、腰围越大(OR=0.954,95%CI=0.916-0.993)、已婚(OR=1.126,95%CI=0.725-1.961)、就业(OR=1.418,95%CI=0.667-3.012)的参与者更有可能属于高健康责任和体力活动风险亚组。
PCOS 患者是一个异质人群,可能存在潜在的亚类,适合采用个性化多层次护理和针对性干预措施。