Hassankhani Amir, Ghozy Sherief, Amoukhteh Melika, Bilgin Cem, Kadirvel Ramanathan, Kallmes David F
Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Department of Radiology, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA, USA.
Interv Neuroradiol. 2023 Jun 26:15910199231184524. doi: 10.1177/15910199231184524.
The Woven EndoBridge (WEB) has been specifically developed to manage wide neck bifurcation intracranial aneurysms. A wide range of aneurysm occlusion rates and device-related complications are reported in different papers, and a lack of collective evidence in this regard.
To clarify the long-term efficacy and safety outcomes of intracranial aneurysm treatment with WEB devices.
A systematic literature search was performed on PubMed, Scopus, Web of Science, and Embase databases on April 25, 2023. Considering the eligibility criteria, all the studies reporting the outcomes of the intracranial aneurysm treatment with WEB device at 1 and/or more than 1 year were included. Data elements of interest were extracted and analyzed using R software version 4.2.1.
Twenty-seven articles were included. Complete occlusion rate was 56.85%, 67.10%, and 56.34% at one year, beyond one year, and at/beyond two years of follow-up, respectively. Adequate occlusion rate was 87.11% at one year, 91.16% beyond one year, and 88.87% at/beyond two years of follow-up. WEB compression and aneurysm recurrence rates increased from 17.62% and 0.58% at one year to 42.59% and 18.99% beyond one year of follow-up, respectively. An increase in retreatment rate from 3.45% at one year to 7.15% beyond one year of follow-up was found.
The current study supports the long-term efficacy of WEB devices for the treatment of intracranial aneurysms. However, an increase in WEB compression, aneurysm recurrence, and retreatment rates beyond one year reveals the importance of follow-ups after the first year of WEB placement.
编织型血管内桥接装置（WEB）专门用于治疗宽颈分叉颅内动脉瘤。不同论文报道了广泛的动脉瘤闭塞率和与装置相关的并发症，且在这方面缺乏综合证据。
阐明使用WEB装置治疗颅内动脉瘤的长期疗效和安全性结果。
于2023年4月25日在PubMed、Scopus、科学网和Embase数据库中进行了系统的文献检索。根据纳入标准，纳入所有报告使用WEB装置治疗颅内动脉瘤1年及/或1年以上结果的研究。使用R软件4.2.1版本提取并分析感兴趣的数据元素。
纳入27篇文章。随访1年、1年以上和2年及/以上时，完全闭塞率分别为56.85%、67.10%和56.34%。随访1年、1年以上和2年及/以上时，充分闭塞率分别为87.11%、91.16%和88.87%。WEB压迫和动脉瘤复发率分别从随访1年时的17.62%和0.58%增加到随访1年以上时的42.59%和18.99%。发现再治疗率从随访1年时的3.45%增加到随访1年以上时的7.15%。
本研究支持WEB装置治疗颅内动脉瘤的长期疗效。然而，随访1年以上时WEB压迫、动脉瘤复发和再治疗率的增加揭示了WEB植入后第1年之后进行随访的重要性。
