Krynicki Carl R, Jones Christopher A, Hacker David A
School of Psychology, The University of Birmingham, Birmingham, UK.
Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, UK.
Appl Neuropsychol Adult. 2025 Jul-Aug;32(4):1205-1222. doi: 10.1080/23279095.2023.2225666. Epub 2023 Jun 26.
Deficits in executive functioning are a common consequence of Traumatic Brain Injury (TBI) and the severity of TBI is known to predict functional outcomes. In this review, the authors examine the ability of three commonly used tests of executive functioning [The Trail Making Test (TMT-B), The Wisconsin Card Sorting Test (WCST), and Verbal Fluency (VF)] to predict domains of function.
Seven hundred and twenty articles were identified and twenty-four met inclusion criteria (original articles published in English examining an adult TBI population). Data were subject to a study quality analysis and then meta-analyzed to assess whether tests of executive functioning (TMT-B, WCST, and VF) can predict functional, employment, and driving outcomes following a TBI.
The TMT-B ( = 0.29; 95% CI 0.17-0.41) and the WCST ( = 0.20; 95% CI 0.02-0.37) were significantly associated with functional outcomes. The TMT-B was also associated with a person's ability to return to driving ( = 0.3890; 95% CI 0.2678-0.5103). No test of executive functioning was associated with employment outcomes following a TBI.
These findings are important to guide rehabilitation strategies and future planning. This review has also highlighted the scarcity of research on specific outcomes.
执行功能缺陷是创伤性脑损伤(TBI)的常见后果,且已知TBI的严重程度可预测功能结局。在本综述中,作者考察了三种常用的执行功能测试[连线测验B(TMT-B)、威斯康星卡片分类测验(WCST)和言语流畅性(VF)]预测功能领域的能力。
共识别出720篇文章,其中24篇符合纳入标准(以英文发表的研究成年TBI人群的原创文章)。对数据进行研究质量分析,然后进行荟萃分析,以评估执行功能测试(TMT-B、WCST和VF)能否预测TBI后的功能、就业和驾驶结局。
TMT-B(r = 0.29;95%CI 0.17 - 0.41)和WCST(r = 0.20;95%CI 0.02 - 0.37)与功能结局显著相关。TMT-B还与人恢复驾驶的能力相关(r = 0.3890;95%CI 0.2678 - 0.5103)。没有执行功能测试与TBI后的就业结局相关。
这些发现对指导康复策略和未来规划很重要。本综述还突出了针对特定结局的研究稀缺性。