使用168菌株生产的“瓦伦西亚烯”（转基因食品和饲料）。
"Valencene" Produced Using 168 strain (Genetically Modified Foods and Feeds).
出版信息
Food Saf (Tokyo). 2023 Jun 23;11(2):34-35. doi: 10.14252/foodsafetyfscj.D-23-00003. eCollection 2023 Jun.
Food Safety Commission of Japan (FSCJ) conducted a safety assessment on a food additive: flavoring "Valencene", which is produced using 168 strain based on documents mainly submitted by the applicant. Safety of the inserted genes including toxicity and allergenicity of the proteins produced from the inserted genes, recombinant and host protein residues, and others were evaluated based on the guideline. In the evaluations no risk due to use of recombinant technology was found in the bio-production of "Valencene". From the identified chemical structures, toxicological findings and also estimated intakes of non-active ingredients detected in "Valencene", none of safety issues were expected for them. From the above evaluations, FSCJ concluded that no concern relevant to human health is raised on the food additive, "Valencene" produced using 168 strain.
日本食品安全委员会（FSCJ）根据申请人主要提交的文件，对一种食品添加剂——使用168菌株生产的调味剂“瓦伦西亚烯”进行了安全性评估。根据该指南，对插入基因的安全性进行了评估，包括插入基因产生的蛋白质的毒性和致敏性、重组蛋白和宿主蛋白残留等。在评估中，未发现“瓦伦西亚烯”生物生产过程中使用重组技术存在风险。根据“瓦伦西亚烯”中鉴定出的化学结构、毒理学结果以及检测到的非活性成分的估计摄入量，预计它们不存在任何安全问题。基于上述评估，FSCJ得出结论，使用168菌株生产的食品添加剂“瓦伦西亚烯”不存在与人类健康相关的问题。
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