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[血液吸附对7天抗立位耐力降低期间及体外试验中血液流变学指标的影响]

[Effect of hemosorption on rheological indicators of blood during 7-day anti-orthostatic hypokinesia and in in vitro tests].

作者信息

Goncharov I B, Ivanov A P, Davydkin A F, Kudriashova Zh M

出版信息

Kosm Biol Aviakosm Med. 1986 May-Jun;20(3):50-3.

PMID:3736006
Abstract

The effect of hemosorption of blood rheology was examined in 9 healthy men exposed to headdown tilt (-8 degrees). Venous-venous hemosorption was performed on tilt day 7 using activated charcoal SKN-2M. It was found that by tilt day 7 rheological parameters increased significantly and returned to the norm after 2-hour hemoperfusion through activated charcoal. This shows that hemosorption produces a beneficial effect on blood rheology and microcirculation which is indicated by a direct examination of eye microvessels. Experimental in vitro studies using oxygenated and nonoxygenated donor's blood demonstrated that hemosorption combined with blood oxygenation can noticeably increase the effectiveness of perfusion on the whole.

摘要

对9名处于头低位倾斜(-8度)的健康男性进行了血液吸附对血液流变学影响的研究。在倾斜第7天使用活性炭SKN-2M进行静脉-静脉血液吸附。结果发现,到倾斜第7天时,流变学参数显著升高,在通过活性炭进行2小时血液灌注后恢复正常。这表明血液吸附对血液流变学和微循环产生有益影响,这一点通过直接检查眼部微血管得以证实。使用含氧和无氧供体血液进行的体外实验研究表明,血液吸附与血液氧合相结合可显著提高整体灌注效果。

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