Hassell Natalie E, Grzeszczak Ewa, Adams Ryan C, Drake Wonder P
Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, United States.
Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, United States.
Case Rep Intern Med. 2020 Mar;7(1):1-5. doi: 10.5430/crim.v7n1p1. Epub 2019 Dec 12.
Pulmonary sarcoidosis is unlikely to resolve if it persists for greater than five years. A growing body of literature supports the involvement of the microbiome in sarcoidosis and a role for sex hormones in pulmonary fibrosis. Additionally, obesity is a risk factor for the development of sarcoidosis. Bariatric surgery is an effective treatment for obesity and can lead to microbial and endocrine changes. Here, we report the clinical improvement of longstanding pulmonary sarcoidosis following sleeve gastrectomy.
如果肺结节病持续超过五年,则不太可能自行消退。越来越多的文献支持微生物群参与结节病以及性激素在肺纤维化中的作用。此外,肥胖是结节病发展的一个危险因素。减肥手术是治疗肥胖的有效方法,可导致微生物和内分泌变化。在此,我们报告了袖状胃切除术后长期肺结节病的临床改善情况。