Cavanaugh S V
Med Clin North Am. 1986 Sep;70(5):1185-202. doi: 10.1016/s0025-7125(16)30919-1.
Psychiatric disorders are common in medical inpatient and outpatient populations. As a result, internists commonly are the first to see psychiatric emergencies. As with all medical problems, a good history, including a collateral history from relatives and friends, physical and mental status examination, and appropriate laboratory tests help establish a preliminary diagnosis and treatment plan. Patients with suicidal ideation usually have multiple stressors in the environment and/or a psychiatric disorder (i.e., a major affective disorder, dysthymic disorder, anxiety or panic disorder, psychotic disorder, alcohol or drug abuse, a personality disorder, and/or an adjustment disorder). Of all patients who commit suicide, 70% have a major depressive disorder, schizophrenia, psychotic organic mental disorder, alcoholism, drug abuse, and borderline personality disorder. Patients who are at great risk have minimal supports, a history of previous suicide attempts, a plan with high lethality, hopelessness, psychosis, paranoia, and/or command self-destructive hallucinations. Treatment is directed toward placing the patient in a protected environment and providing psychotropic medication and/or psychotherapy for the underlying psychiatric problem. Other psychiatric emergencies include psychotic and violent patients. Psychotic disorders fall into two categories etiologically: those that have an identifiable organic factor causing the psychosis and those that have an underlying psychiatric disorder. Initially, it is essential to rule out organic pathology that is life-threatening or could cause irreversible brain damage. After such organic causes are ruled out, neuroleptic medication is indicated. If the patient is not agitated or combative, he or she may be placed on oral divided doses of neuroleptics in the antipsychotic range. Patients who are agitated or psychotic need rapid tranquilization with an intramuscular neuroleptic every half hour to 1 hour until the agitation and combativeness are under control. Haloperidol (Haldol) is the safest neuroleptic. Chlorpromazine (Thorazine), perphenazine (Trilafon), and, in the elderly, thiothixene (Navane) can also be useful if haloperidol (Haldol) is not effective and more sedation is needed; these drugs, however, produce more side effects. Violent patients need to be physically restrained and then given antipsychotic medication or, in the case of drug abuse or alcohol withdrawal, the appropriate drug management.(ABSTRACT TRUNCATED AT 250 WORDS)
精神障碍在医学住院患者和门诊患者中很常见。因此,内科医生通常是最先诊治精神科急症的人。与所有医疗问题一样,详细的病史,包括来自亲属和朋友的旁证病史、体格和精神状态检查以及适当的实验室检查,有助于确立初步诊断和治疗方案。有自杀意念的患者通常在环境中存在多种应激源和/或患有精神障碍(即重度情感障碍、心境恶劣障碍、焦虑或惊恐障碍、精神障碍、酒精或药物滥用、人格障碍和/或适应障碍)。在所有自杀的患者中,70%患有重度抑郁症、精神分裂症、器质性精神障碍、酒精中毒、药物滥用和边缘性人格障碍。高危患者的支持系统极少,有过自杀未遂史,有高致死性的计划,感到绝望、患有精神病、偏执狂和/或有命令性自我毁灭幻觉。治疗的方向是将患者置于受保护的环境中,并针对潜在的精神问题提供精神药物和/或心理治疗。其他精神科急症包括精神病患者和暴力患者。精神障碍在病因上分为两类:一类有可识别的导致精神病的器质性因素,另一类有潜在的精神障碍。首先,必须排除危及生命或可能导致不可逆脑损伤的器质性病变。排除这些器质性病因后,需使用抗精神病药物。如果患者不烦躁或不具攻击性,可给予抗精神病范围内的口服分次剂量的抗精神病药物。烦躁或有精神病的患者需要每半小时至1小时肌肉注射一次抗精神病药物进行快速镇静,直至烦躁和攻击性得到控制。氟哌啶醇(哈力多)是最安全的抗精神病药物。如果氟哌啶醇(哈力多)无效且需要更多镇静作用,氯丙嗪(氯普马嗪)、奋乃静(三氟拉嗪)以及老年人使用的硫利达嗪(甲硫达嗪)也可能有用;然而,这些药物会产生更多副作用。暴力患者需要进行身体约束,然后给予抗精神病药物,或者在药物滥用或酒精戒断的情况下,进行适当的药物处理。(摘要截选至250词)