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超声检查与临床诊断——在诊断急性阑尾炎方面哪种方法更好?一项队列研究

Ultrasound vs. clinical diagnosis-which is better in diagnosing acute appendicitis?: a cohort study.

作者信息

Kam Cheuk Tung, Alsahaf Mahdi, Chongbang Kul, Taki Mona, Yusob Jamal, Alexander Santhosh, Rait Jaideep

机构信息

Department of General Surgery, Maidstone and Tunbridge Wells NHS Trust.

William Harvey Hospital, East Kent University Hospital NHS Foundation Trust.

出版信息

Ann Med Surg (Lond). 2023 May 4;85(6):2336-2340. doi: 10.1097/MS9.0000000000000730. eCollection 2023 Jun.

Abstract

UNLABELLED

Acute appendicitis is one of the most common causes of right iliac fossa pain which often warrants surgical management. In many cases, abdominal ultrasonography (USS) is done to confirm the diagnosis however negative appendicectomy is common due to atypical presentations and different visualisation rate. The unnecessary operative intervention can result in complications. The aim of this study was to compare the efficacy between clinical diagnosis and USS in diagnosing acute appendicitis to avoid negative appendicectomy and prevent further complications.

METHOD

A retrospective cohort study was conducted in a district general hospital which 1046 cases of laparoscopic appendicectomy were included and examined for the use of USS or clinical diagnosis. The sensitivity, specificity, negative and positive predictive value in USS and data in clinical evaluation were analysed for their accuracy in the diagnosis of acute appendicitis based on the histology results post appendicectomy.

RESULTS

Clinical diagnosis without preoperative imaging was found to have a significantly lower negative appendicectomy rate of 27.20% compared with 42.67% in those who underwent ultrasound. 44.64% of the patients were misdiagnosed with a normal USS result who had a subsequent positive histology of appendicitis.

CONCLUSIONS

USS has been shown to be less sensitive for diagnosing acute appendicitis which results in high negative appendicectomy and misdiagnosis rate. With an increasing burden of health budget and resources, cautious and appropriate use of USS would avoid the misdiagnosis and prevent further complications. Thorough clinical evaluation remains an important first step and role in the diagnosis of acute appendicitis.

摘要

未标注

急性阑尾炎是引起右下腹疼痛最常见的原因之一,常需手术治疗。在许多情况下,会进行腹部超声检查(USS)以确诊,但由于表现不典型和不同的可视化率,阴性阑尾切除术很常见。不必要的手术干预可能导致并发症。本研究的目的是比较临床诊断和超声检查在诊断急性阑尾炎方面的疗效,以避免阴性阑尾切除术并预防进一步的并发症。

方法

在一家地区综合医院进行了一项回顾性队列研究,纳入1046例行腹腔镜阑尾切除术的病例,并检查其超声检查或临床诊断的使用情况。根据阑尾切除术后的组织学结果,分析超声检查的敏感性、特异性、阴性和阳性预测值以及临床评估数据在诊断急性阑尾炎方面的准确性。

结果

发现术前未进行影像学检查的临床诊断的阴性阑尾切除率显著较低,为27.20%,而接受超声检查的患者为42.67%。44.64%的患者超声检查结果正常但被误诊,随后阑尾组织学检查呈阳性。

结论

超声检查对诊断急性阑尾炎的敏感性较低,导致阴性阑尾切除率和误诊率较高。随着卫生预算和资源负担的增加,谨慎且适当地使用超声检查可避免误诊并预防进一步的并发症。全面的临床评估仍然是诊断急性阑尾炎的重要第一步和关键环节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91d5/10289541/534b6917ab3c/ms9-85-2336-g001.jpg

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