酒精最低限价对酒精依赖治疗处方的影响：一项对照中断时间序列分析

The Effect of Minimum Unit Pricing for Alcohol on Prescriptions for Treatment of Alcohol Dependence: A Controlled Interrupted Time Series Analysis.

作者信息

Manca Francesco, Zhang Lisong, Fitzgerald Niamh, Mackay Daniel, McAuley Andrew, Sharp Clare, Lewsey Jim

机构信息

School of Health and Wellbeing. UK, University of Glasgow, 1 Lilybank Gardens, Glasgow, G12 8RZ UK.

Institute for Social Marketing and Health (ISM). UK, University of Stirling, Stirling, UK.

出版信息

Int J Ment Health Addict. 2023 May 22:1-16. doi: 10.1007/s11469-023-01070-6.

DOI:10.1007/s11469-023-01070-6

PMID:37363757

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10202053/

Abstract

UNLABELLED

In 2018, Scotland introduced a minimum unit price (MUP) for alcohol to reduce alcohol-related harms. We aimed to study the association between MUP introduction and the volume of prescriptions to treat alcohol dependence, and volume of new patients receiving such prescriptions. We also examined whether effects varied across different socio-economic groups. A controlled interrupted time series was used to examine variations of our two outcomes. The same prescriptions in England and prescriptions for methadone in Scotland were used as controls. There was no evidence of an association between MUP implementation and the volume of prescriptions for alcohol dependence (immediate change: 2.74%, 95% CI: -0.068 0.014; slope change: 0% 95%CI: -0.001 0.000). A small, significant increase in slope in number of new patients receiving prescriptions was observed (0.2% 95%CI: 0.001 0.003). However, no significant results were confirmed after robustness checks. We found also no variation across different socioeconomic groups.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s11469-023-01070-6.

摘要

未标注

2018年，苏格兰引入了酒精最低单位价格（MUP）以减少与酒精相关的危害。我们旨在研究引入MUP与治疗酒精依赖的处方量以及接受此类处方的新患者数量之间的关联。我们还研究了不同社会经济群体的影响是否存在差异。采用对照中断时间序列来研究我们两个结果的变化情况。将英格兰的相同处方和苏格兰的美沙酮处方用作对照。没有证据表明实施MUP与酒精依赖处方量之间存在关联（即时变化：2.74%，95%置信区间：-0.068至0.014；斜率变化：0%，95%置信区间：-0.001至0.000）。观察到接受处方的新患者数量斜率有小幅显著增加（0.2%，95%置信区间：0.001至0.003）。然而，在进行稳健性检验后未确认有显著结果。我们还发现不同社会经济群体之间没有差异。