University of Central Florida, College of Medicine, Orlando, USA.
Orlando Immunology Center, Orlando, FL, USA.
J Investig Med. 2023 Dec;71(8):946-952. doi: 10.1177/10815589231182313. Epub 2023 Jun 26.
Prior studies demonstrate that non-White patients are less likely to achieve human immunodeficiency virus (HIV) suppression compared to White patients due to lack of health insurance. This study aims to determine whether racial disparities in the HIV care cascade persist among a cohort of privately and publicly insured patients. This retrospective analysis evaluated HIV care outcomes during the first year of care. Eligible patients were aged 18-65 years, treatment-naïve, and seen between 2016 and 2019. Demographic and clinical variables were extracted from the medical record. Differences in the proportion of patients achieving each HIV care cascade stage by race were evaluated using unadjusted chi-square testing. Risk factors for viral non-suppression at 52 weeks were analyzed using multivariate logistic regression. We included 285 patients; ninety-nine were White, 101 were Black, and 85 identified as Hispanic/LatinX ethnicity. Significant differences in retention in care for Hispanic/LatinX patients (odds ratio (OR): 0.214, 95% confidence interval (CI): 0.067-0.676) and viral suppression for both Black (OR: 0.348, 95% CI: 0.178, 0.682) and Hispanic/LatinX patients (OR: 0.392, 95% CI: 0.195, 0.791) compared to White patients were observed. In multivariate analyses, Black patients were less likely to achieve viral suppression compared to White patients (OR: 0.464, 95% CI: 0.236, 0.902). This study showed that non-White patients were less likely to achieve viral suppression after 1 year despite insurance and suggests that other unmeasured factors may disproportionately affect viral suppression in these patients. Interventions to identify and address these factors are needed to improve HIV care outcomes for non-White populations.
先前的研究表明,由于缺乏医疗保险,非白种人患者比白种人患者更难以实现人类免疫缺陷病毒 (HIV) 抑制。本研究旨在确定在私人和公共保险患者队列中,HIV 护理级联中的种族差异是否仍然存在。这项回顾性分析评估了护理开始后第一年的 HIV 护理结果。符合条件的患者年龄在 18-65 岁之间,为初次接受治疗,就诊时间为 2016 年至 2019 年。从病历中提取人口统计学和临床变量。使用未调整的卡方检验评估不同种族患者达到每个 HIV 护理级联阶段的比例差异。使用多变量逻辑回归分析 52 周时病毒未抑制的风险因素。我们纳入了 285 名患者;其中 99 名是白人,101 名是黑人,85 名是西班牙裔/拉丁裔。与白人患者相比,西班牙裔/拉丁裔患者在护理保留方面(优势比 (OR):0.214,95%置信区间 (CI):0.067-0.676)和病毒抑制方面(黑人 OR:0.348,95% CI:0.178,0.682)以及西班牙裔/拉丁裔患者(OR:0.392,95% CI:0.195,0.791)均存在显著差异。在多变量分析中,与白人患者相比,黑人患者实现病毒抑制的可能性较小(OR:0.464,95% CI:0.236,0.902)。本研究表明,尽管有保险,非白种人患者在 1 年后仍不太可能实现病毒抑制,这表明其他未测量的因素可能会不成比例地影响这些患者的病毒抑制。需要采取干预措施来识别和解决这些因素,以改善非白人群体的 HIV 护理结果。