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髋部骨折类型的预测因素:系统评价。

Predictor of hip fracture type: a systematic review.

机构信息

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Università Cattolica del Sacro Cuore Roma.

出版信息

Acta Biomed. 2023 Jun 23;94(S2):e2023047. doi: 10.23750/abm.v94iS2.12572.

Abstract

BACKGROUND & AIM In literature, many risk factors have been related to proximal femur fracture, but most of the studies do not explore differences between femoral neck fractures (FNF) and pertrochanteric fractures (PF). The aim of the paper is to review the current literature n order to assess risk factors associated with a specific pattern of proximal femur fracture.   METHODS Nineteen studies met the inclusion criteria and were taken into consideration in the review. Data reported from the included articles were age, gender of the patient, type of femoral fracture, BMI, height, weight, soft tissue composition, BMD, vitamin D levels, PTH levels, hip morphology and hip osteoarthritis.   RESULTS Bone mineral density (BMD) of the intertochanteric region result significant lower in PF, while BMD in femoral neck regione was lower in FNF. Low levels of Vit D with high PTH are observed in TF whereas low levels of vit D and normal PTH in FNF. Hip osteoarthritis (HOA) is significant less present and less severe in FNF, while in PF is usually more frequent or higher grade.   CONCLUSIONS Patients with pertrochanteric fracture are older, with a low cortical thickness in the femoral isthmus, low BMD in the intertrochanteric region, severe HOA, low mean haemoglobin and albumin levels and hypovitaminosis D with a high PTH levels. Patients with FNF are younger, taller, with higher body fat mass, with lower BMD levels in femoral neck region, mild HOA, hypovitaminosis D without PTH response.

摘要

背景与目的

文献中报道了许多与股骨近端骨折相关的危险因素,但大多数研究并未探讨股骨颈骨折(FNF)和转子间骨折(PF)之间的差异。本文旨在回顾当前文献,以评估与特定类型股骨近端骨折相关的危险因素。

方法

符合纳入标准的 19 项研究被纳入综述。纳入文章中报告的数据包括患者年龄、性别、股骨骨折类型、BMI、身高、体重、软组织成分、BMD、维生素 D 水平、PTH 水平、髋关节形态和髋关节炎。

结果

PF 患者的转子间区域骨密度(BMD)显著降低,而 FNF 患者的股骨颈区域 BMD 降低。TF 中存在低 Vit D 和高 PTH,而 FNF 中存在低 Vit D 和正常 PTH。FNF 中髋关节骨关节炎(HOA)的发生率较低且程度较轻,而在 PF 中则更为常见或程度更高。

结论

转子间骨折患者年龄较大,股骨干骺端皮质厚度较薄,转子间区域 BMD 较低,严重 HOA,平均血红蛋白和白蛋白水平较低,维生素 D 缺乏伴高 PTH 水平。FNF 患者较年轻,身高较高,体脂质量较高,股骨颈区域 BMD 水平较低,HOA 较轻,维生素 D 缺乏而无 PTH 反应。

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