Sleep Research Clinic and Laboratory, Department of Psychology, The University of Hong Kong, Hong Kong, China.
Shanghai Mental Health Center, Shanghai, China.
J Sleep Res. 2024 May;33(3):e13967. doi: 10.1111/jsr.13967. Epub 2023 Jun 27.
Sleep variability is commonly seen in the young populations. This study aimed to examine the impacts of experimentally induced sleep variability on sleepiness, mood, cognitive performance and sleep architectures among young adults. Thirty-six healthy individuals (aged 18-22 years) were randomly assigned to either variable sleep schedule (n = 20) or control (n = 16) groups. The protocol involved 1 week of regular sleep (time in bed = 7.5 hr) in the home setting, followed by one adaptation night (time in bed = 7.5 hr), one baseline night (time in bed = 7.5 hr), and 6 nights of sleep manipulation in the laboratory monitored by polysomnography (three cycles of variable sleep schedule by changing daily time in bed alternating between 6 hr and 9 hr for variable sleep schedule group versus fixed sleep schedule with daily time in bed for 7.5 hr for control group). Sleepiness, mood, sustained attention, processing speed, response inhibition and working memory were measured every morning and evening. The variable sleep schedule group reported a higher level of sleepiness, especially in the mornings, and increased negative mood in the evenings. There were no significant differences in positive mood, cognitive performance and sleep macro- and micro-structures. Our results showed the negative effects of sleep variability on daytime functioning especially sleepiness and negative mood, suggesting the need to address variable sleep schedules through sleep intervention.
睡眠变异性在年轻人群中很常见。本研究旨在探讨实验诱导的睡眠变异性对年轻成年人的嗜睡、情绪、认知表现和睡眠结构的影响。36 名健康个体（年龄 18-22 岁）被随机分配到可变睡眠时间表组（n=20）或对照组（n=16）。该方案包括在家中进行 1 周的正常睡眠（卧床时间=7.5 小时），随后进行 1 个适应期（卧床时间=7.5 小时），1 个基线期（卧床时间=7.5 小时），以及在实验室中通过多导睡眠图监测的 6 个睡眠操作期（可变睡眠时间表组通过每天的睡眠时间在 6 小时和 9 小时之间交替来改变睡眠时间表，进行 3 个周期的可变睡眠时间表，而对照组则保持每天 7.5 小时的固定睡眠时间）。每天早晚测量嗜睡、情绪、持续注意力、处理速度、反应抑制和工作记忆。可变睡眠时间表组报告的嗜睡程度更高，尤其是在早上，晚上的负面情绪增加。积极情绪、认知表现和睡眠宏观结构和微观结构没有显著差异。我们的结果表明，睡眠变异性对白天功能，特别是嗜睡和负面情绪有负面影响，这表明需要通过睡眠干预来解决可变睡眠时间表的问题。
